CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019977
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gamma-glutamyltransferase 7 
Protein Synonyms/Alias
 GGT 7; Gamma-glutamyltransferase-like 3; Gamma-glutamyltranspeptidase 7; Glutathione hydrolase 7; Gamma-glutamyltransferase 7 heavy chain; Gamma-glutamyltransferase 7 light chain 
Gene Name
 Ggt7 
Gene Synonyms/Alias
 Ggtl3 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
45AAPLRGRKDEDAFLGubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Cleaves glutathione conjugates (By similarity). 
Sequence Annotation
 MOD_RES 83 83 Phosphoserine (By similarity).
 CARBOHYD 198 198 N-linked (GlcNAc...) (Potential).
 CARBOHYD 267 267 N-linked (GlcNAc...) (Potential).
 CARBOHYD 283 283 N-linked (GlcNAc...) (Potential).
 CARBOHYD 330 330 N-linked (GlcNAc...) (Potential).
 CARBOHYD 353 353 N-linked (GlcNAc...) (Potential).
 CARBOHYD 394 394 N-linked (GlcNAc...) (Potential).
 CARBOHYD 519 519 N-linked (GlcNAc...) (Potential).
 CARBOHYD 523 523 N-linked (GlcNAc...) (Potential).
 CARBOHYD 586 586 N-linked (GlcNAc...) (Potential).  
Keyword
 Acyltransferase; Complete proteome; Glutathione biosynthesis; Glycoprotein; Hydrolase; Membrane; Phosphoprotein; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix; Zymogen. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 662 AA 
Protein Sequence
MAAENEASQE SALGAYSPVD YMSITSFPRL PEDEPAPAAP LRGRKDEDAF LGDPDTDPDS 60
FLKSARLQRL PSSSSEMGSQ DGSPLRETRK DPFSAAAAEC SCRQDGLTVI VTACLTFATG 120
VTVALVMQIY FGDPQIFQQG AVVTDASCCT ALGMEVLSKQ GSSVDAAVAA ALCLGIVAPH 180
SSGLGGGGVM LVHDIRRNES HLIDFRESAP GALREEALQR SWDTKPGLLV GVPGMVKGLY 240
EAHQLYGRLP WSQVLAFAAA VAQDGFNVTH DLAHALAEQL PPNASDRFLE TFLPLGHPPL 300
PGSLLRRPDL AEVLDILGIS GPAAFYNGGN LTLEMVAEVQ HAGGVMTEED FSNYSALTEK 360
PVCGVYRGHL VLSPPPPHTG PALISALNIL EGFNLTSLVS REQALHWVAE TLKIALALAS 420
RLGDPVYDST ISESMDDMLS KVEAANFRGH ISDSQAAPAP LLPVYELDGA PTAAQVLVMG 480
PDDFIVAMVS SLNRPFGSGL LTPSGILLNS QMLDFSWPNR TANHSAPSLE NSVQPGKRPL 540
SFLLPTVVRP AEGLCGTYLA LGANGAARGL SGLTQVLLNV LTLNRNLSDS LARGRLHPDL 600
QSNVLQVDSE FTEEEIEFLE ARGHHVEKVD VLSWVHGSRR TNNFIIGVKD PRSLDATGAS 660
IL 662 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0003840; F:gamma-glutamyltransferase activity; IEA:EC.
 GO:0036374; F:glutathione hydrolase activity; IEA:EC.
 GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR000101; GGT_peptidase. 
Pfam
 PF01019; G_glu_transpept 
SMART
  
PROSITE
 PS00462; G_GLU_TRANSPEPTIDASE 
PRINTS
 PR01210; GGTRANSPTASE.