UniProt Accession

 A0SZW2_RAT; A0SZW2 

Genbank Protein ID

 AABR06109279; AABR06109280; EF066490; CH474106 

Genbank Nucleotide ID

 ABK59325.1; EDL75129.1 

Protein Name

 CD40 ligand 

Protein Synonyms/Alias

 CD40 ligand CD154 

Gene Name

 Cd40lg 

Gene Synonyms/Alias

 rCG_39232 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
105	ISLNKEEKKEKSFEM	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Cytokine; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 260 AA 

Protein Sequence

Gene Ontology

 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
 GO:0030183; P:B cell differentiation; IEA:Compara.
 GO:0042100; P:B cell proliferation; IEA:Compara.
 GO:0048305; P:immunoglobulin secretion; IEA:Compara.
 GO:0006954; P:inflammatory response; IEA:Compara.
 GO:0045190; P:isotype switching; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0030168; P:platelet activation; IEA:Compara.
 GO:2000353; P:positive regulation of endothelial cell apoptotic process; IEA:Compara.
 GO:0032735; P:positive regulation of interleukin-12 production; IEA:Compara.
 GO:0051023; P:regulation of immunoglobulin secretion; IEA:Compara. 

Interpro

 IPR006052; TNF.
 IPR021184; TNF_CS.
 IPR003263; TNF_ligand_5.
 IPR008983; Tumour_necrosis_fac-like_dom. 

Pfam

 PF00229; TNF 

SMART

 SM00207; TNF 

PROSITE

 PS00251; TNF_1
 PS50049; TNF_2 

PRINTS

 PR01702; CD40LIGAND.