CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016464
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA-binding protein 45 
Protein Synonyms/Alias
 Developmentally-regulated RNA-binding protein 1; RB-1; RNA-binding motif protein 45 
Gene Name
 Rbm45 
Gene Synonyms/Alias
 Drb1; Drbp1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
237SEFSTFDKNDSRGQEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 RNA-binding protein with binding specificity for poly(C). May play an important role in neural development (By similarity). 
Sequence Annotation
 DOMAIN 26 106 RRM 1.
 DOMAIN 121 192 RRM 2.
 DOMAIN 392 464 RRM 3.  
Keyword
 Complete proteome; Cytoplasm; Developmental protein; Differentiation; Neurogenesis; Nucleus; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 476 AA 
Protein Sequence
MDDAGGLGGS GGFRPGVDSL DEPPNSRIFL VISKHTSELV LRERFSPFGD IQDIWVVRDK 60
HTKESKGVAF VKFARSSQAC RAMEEMHGQC LGPSDTKPIK VFIAQSRSSG SHRDVEDEEL 120
TRIFVMIPKS YTEEDLREKF KVYGDIEYCS IIKNKVTGES KGLGYVRYLK PSQAAQAIEN 180
CDRSFRALLA EPKNKVSGSP EQDDYSSGRQ EALGQEPRAN LFPFVGEQQS EFSTFDKNDS 240
RGQEAVSKRL SVVSRVPFTE EQLFSIFDIV PGLEYCEVPR DPYSNYGHGV VQYFNVASAI 300
YAKYKLHGFQ YPPGNRIVVS FLDDGSNMTE LIRKMATQMV AAQLASMVWS TTSQQQFLQY 360
GGNAASQAPQ IQTDVVLPSC KKKAPPETPV KERLFVVFNP HPLPLDVLED IFCRFGNLIE 420
VYLVSGKNVG YVKYADRKSA NEAITTLHGK ILNGVRLKVM LADSPREESK KRQRTY 476 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; ISS:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007399; P:nervous system development; ISS:UniProtKB. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS