| Tag | Content |
|---|
| CPLM ID | CPLM-023484 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier family 22 member 21 |
Protein Synonyms/Alias | Organic cation/carnitine transporter 3; Solute carrier family 22 member 9 |
Gene Name | Slc22a21 |
Gene Synonyms/Alias | Octn3; Slc22a9 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 291 | LISQGRIKEAEVIIR | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Sodium-ion independent, medium affinity carnitine transporter. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 746. |
Sequence Annotation | NP_BIND 218 225 ATP (Potential).
CARBOHYD 57 57 N-linked (GlcNAc...) (Potential).
CARBOHYD 64 64 N-linked (GlcNAc...) (Potential).
CARBOHYD 91 91 N-linked (GlcNAc...) (Potential). |
Keyword | ATP-binding; Complete proteome; Glycoprotein; Ion transport; Membrane; Nucleotide-binding; Peroxisome; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 564 AA |
Protein Sequence | MLDYDEVTAF LGEWGTFQRL IFFLLSASII PNGFTGLSAV FLTAIPEHRC RIPDTVNLSS 60
AWRNHSIPME TKDGPEVPQK CRRYRLATIA NFSELGLEPG RDVDLEQLEQ ENCLDGWEYD 120
KDIFLSTIVT EWDLVCKDDW KAPLTTSFFY VGVLLGSFIS GQLSDRFGRK NILFLTMAMH 180
TGFSFIQVFS VNFEMFTLLY TLVGMGHISN YVAAFVLGTE MLSKSVRIIF ATLGVCIFFA 240
FGFMVLPLFA YFIREWRRLL LAITLPGVLC GALWWFIPES PRWLISQGRI KEAEVIIRKA 300
AKINGIVAPS TIFDPSETNK LQDDSSKKPQ SHHIYDLVRT PNIRILTIMS IILWLTISVG 360
YFGLSLDTPN LNGNIYVNCF LLAAVEVPAY VLAWLLLQHV SRRYSMAGSL FLGGSVLLLV 420
QLVPSDLHYL STTLVMVGKF GITSAYSMVY VYTAELYPTV VRNMGVGVSS TASRLGSILS 480
PYFVYLGAYD RRLPYILMGS LTILTAIITL FFPESSGVSL PETIDEMQKV KKLKQRQSLS 540
KKGSPKESKG NVSRTSRTSE PKGF 564 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031231; C:intrinsic to peroxisomal membrane; IDA:UniProtKB. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0015226; F:carnitine transmembrane transporter activity; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |