CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016489
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 F-box only protein 30 
Protein Synonyms/Alias
  
Gene Name
 Fbxo30 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
160PREQISVKSSVQEIPubiquitination[1]
371EKDLCWKKVDLGDLKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity). 
Sequence Annotation
 DOMAIN 611 659 F-box.
 ZN_FING 49 110 TRAF-type.  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Ubl conjugation pathway; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 746 AA 
Protein Sequence
MEEEVQQHSH CMNCVSRRCM TRPEPGVSCD LIGCPLVCGA VFHSCKADEH RLLCPFERVA 60
CLNRNFGCPF TLARNKVAEH LEMCPASVVC CTMEWNRWPV SYSDRKSYES LSRDVDEVAQ 120
LDMALALQDQ RMLLESLKVA TMMSKATDKI SEPREQISVK SSVQEIPRTN GLVSVDEESY 180
GALYQATVET TRSLAAALDI LNSATRDIGM LNTSLHATAN EMDEENNKES FQDKNLKDQD 240
HLDEGEIGAV GGVDYSGTSQ NAQAEQNGSS DLLCDLNPSS NGTSALCNGF PLEKMCIQVK 300
GQDQNFHGDS TESNITNGDC VEADGTSEPS SSLVVPEQLR EISPFSALPD STFQQILMPD 360
EDDEKDLCWK KVDLGDLKDV NGSPFSHAPS FKFLSNSWYI PKEDKAVDTS DLEVAEDPMG 420
LQGIDLITAA LLFCLGDSPG GRGISDSRMT DVYHVDFGTQ TFSLPSAILA TNTMVGEIAS 480
ASACDHANPQ LSNPSPFQTL GLDLVLECVA RYQPKQRSMF TFVCGQLFRR KEFSSHFKNV 540
HGDIHAGLNG WMEQRCPLAY YGCTYSQRRF CPSTQGAKII HDRHLRSFGV QPCVSTVLEE 600
PSRNCVLGLR SDHLSSLPFE VLQHIAGFLD GFSLCQLACV SRLMRDVCGS LLQSRGMVIL 660
QWGKKKYPEG NSSWQIKEKV WRFSTAFCSV NDWKFADILS MADHLKNCSY NVIEKREEAI 720
PLPCMCVTRE LTKEGRSLRS VLKPVL 746 
Gene Ontology
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001810; F-box_dom_cyclin-like.
 IPR013323; SIAH-type.
 IPR008974; TRAF-like.
 IPR001293; Znf_TRAF. 
Pfam
 PF00646; F-box 
SMART
  
PROSITE
 PS50181; FBOX
 PS50145; ZF_TRAF 
PRINTS