CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034288
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptojanin-1 
Protein Synonyms/Alias
  
Gene Name
 Synj1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
295TLKDLYGKQIVVNLLubiquitination[1]
414EALGLAEKPQLVTRFubiquitination[1]
495LNSDLADKARALLTTubiquitination[1]
513RASSKVLKNMCENFYubiquitination[1]
541TWNVNGGKQFRSIAFubiquitination[1]
572GIQEFQDKRSKPTDIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 693 AA 
Protein Sequence
MAFSKGFRIY HKLDPPPFSL IVETRHKEEC LMFESGAVAV LSSAEKEAIK GTYAKVLDAY 60
GLLGVLRLNL GDTMLHYLVL VTGCMSVGKI QESEVFRVTS TEFISLRVDA SDEDRISEVR 120
KVLNSGNFYF AWSASGVSLD LSLNAHRSMQ EHTTDNRFFW NQSLHLHLKH YGVNCDDWLL 180
RLMCGGVEIR TIYAAHKQAK ACLISRLSCE RAGTRFNVRG TNDDGHVANF VETEQVIYLD 240
DCVSSFIQIR GSVPLFWEQP GLQVGSHRVR MSRGFEANAP AFDRHFRTLK DLYGKQIVVN 300
LLGSKEGEHM LSKAFQSHLK ASEHASDIHM VSFDYHQMVK GGKAEKLHSI LKPQVQKFLD 360
YGFFYFDGSE VQRCQSGTVR TNCLDCLDRT NSVQAFLGLE MLAKQLEALG LAEKPQLVTR 420
FQEVFRSMWS VNGDSISKIY AGTGALEGKA KAGKLKDGAR SVTRTIQNNF FDSSKQEAID 480
VLLLGNTLNS DLADKARALL TTGSLRASSK VLKNMCENFY KYSKPKKIRV CVGTWNVNGG 540
KQFRSIAFKN QTLTDWLLDA PKLAGIQEFQ DKRSKPTDIF AIGFEEMVEL NAGNIVNAST 600
TNQKLWAVEL QKTISRDNKY VLLASEQLVG VCLFVFIRPQ HAPFIRDVAV DTVKTGMGGA 660
TGNKGAVAIR MLFHTTSLCF VCSHFAAGQS QVK 693 
Gene Ontology
 GO:0030118; C:clathrin coat; TAS:MGI.
 GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.
 GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.
 GO:0007612; P:learning; IMP:MGI.
 GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.
 GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.
 GO:0016082; P:synaptic vesicle priming; IMP:MGI.
 GO:0016191; P:synaptic vesicle uncoating; IMP:MGI. 
Interpro
 IPR005135; Endo/exonuclease/phosphatase.
 IPR000300; IPPc.
 IPR002013; Syja_N. 
Pfam
 PF03372; Exo_endo_phos
 PF02383; Syja_N 
SMART
 SM00128; IPPc 
PROSITE
 PS50275; SAC 
PRINTS