CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035372
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
10PAGILNGKVVSAQIRacetylation[1]
71GIKATHIKLPRTSTEacetylation[1]
315QYNKLNLKTPVPSDIacetylation[1]
475HELTQTDKALFNRLVacetylation[1]
490PSVNGVRKFSDIQIRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 926 AA 
Protein Sequence
MAPAGILNGK VVSAQIRNLL KTQFTQMQEQ VPGFTPGLAI LQVGDRDDSN LYINVKLKAA 60
EEIGIKATHI KLPRTSTESE VLKYIISLNE DATVHGFMVQ LPLDSENSIN TEVVINAIAP 120
EKDVDGLTSI NAGKLARGDL NDCFILCTPK GCLELIKETG VQIAGRHTVV VVVGRSKRVG 180
APMHDLLLWN NATVTTCHSK TANLDKEVNK GDILVVATGQ PEMVKGELIK PGAVVIDCGI 240
NCVPDDTKPS GRKIVGDVAY DEAKEKASFI TPVPDGVGPM TVAILMQSTV ESAQCFLKKF 300
KPGKWTVQYN KLNLKTPVPS DIAISRSCKP KLICNLAREI GLLTEEVELY GETKAKVLLS 360
ALDHLKHRPD GKYVVVTGIT PTPLGEGKST TTIGLVQALG AHLHQNVFAC VQQPSQGPTF 420
GIKGGAAGGG YSQVILMEEF NLHHTGDIHA ITAANNLVAA AIDTRIFHEL TQTDKALFNR 480
LVPSVNGVRK FSDIQIRRLR RLGIEKTDPA ALTDDEINRF ARLDIDPETI TWQRVLDTND 540
RFLRKITIGQ APTEKGHTRT AQFDISVASE IMAVLALTSS LEDMRARLGK MVVASNKKGE 600
PISCEDLGVS GALTVLMKDV IKPNLMQTLE GTPVFVHAGP FTNIAHGNSS IIADWIALKL 660
VGPEGFVVTE AGFGADIGME KFFNIKCRYS GLQPHLVVLV ATVRALKMHG GAGLPLPKAY 720
TEEDLDLVEK GFSNLRKQIE NAKMFGVPVV VAMNAFKTDT DAELDLIGCL SREHGAFNAV 780
KCTHWAEGGQ GALALARAVH RASQAPSSFQ LLYDLKLSVE DKIRIIAQKI YGADDIELLP 840
EAQNKAEIYT KQGFGNLPIC MAKHNPEQKG VPTGFFLPIR DIRASVGAGF LYPLVGTMST 900
MPGLPTQPCF YDIDLDPETE QVNGLF 926 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:InterPro.
 GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:InterPro.
 GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro. 
Interpro
 IPR000559; Formate_THF_ligase.
 IPR020628; Formate_THF_ligase_CS.
 IPR016040; NAD(P)-bd_dom.
 IPR027417; P-loop_NTPase.
 IPR000672; THF_DH/CycHdrlase.
 IPR020630; THF_DH/CycHdrlase_cat_dom.
 IPR020867; THF_DH/CycHdrlase_CS.
 IPR020631; THF_DH/CycHdrlase_NAD-bd_dom. 
Pfam
 PF01268; FTHFS
 PF00763; THF_DHG_CYH
 PF02882; THF_DHG_CYH_C 
SMART
  
PROSITE
 PS00721; FTHFS_1
 PS00722; FTHFS_2
 PS00766; THF_DHG_CYH_1 
PRINTS
 PR00085; THFDHDRGNASE.