CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005245
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-binding/permease protein CydC 
Protein Synonyms/Alias
  
Gene Name
 cydC 
Gene Synonyms/Alias
 mdrA; mdrH; surB; b0886; JW0869 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
102LRIYTFSKLLPLSPAacetylation[1]
321ISDLTDQKPEVTFPDacetylation[1]
570QGRYYQFKQGL****acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system. 
Sequence Annotation
 DOMAIN 18 306 ABC transmembrane type-1.
 DOMAIN 339 572 ABC transporter.
 NP_BIND 373 380 ATP (Potential).  
Keyword
 ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 573 AA 
Protein Sequence
MRALLPYLAL YKRHKWMLSL GIVLAIVTLL ASIGLLTLSG WFLSASAVAG VAGLYSFNYM 60
LPAAGVRGAA ITRTAGRYFE RLVSHDATFR VLQHLRIYTF SKLLPLSPAG LARYRQGELL 120
NRVVADVDTL DHLYLRVISP LVGAFVVIMV VTIGLSFLDF TLAFTLGGIM LLTLFLMPPL 180
FYRAGKSTGQ NLTHLRGQYR QQLTAWLQGQ AELTIFGASD RYRTQLENTE IQWLEAQRRQ 240
SELTALSQAI MLLIGALAVI LMLWMASGGV GGNAQPGALI ALFVFCALAA FEALAPVTGA 300
FQHLGQVIAS AVRISDLTDQ KPEVTFPDTQ TRVADRVSLT LRDVQFTYPE QSQQALKGIS 360
LQVNAGEHIA ILGRTGCGKS TLLQQLTRAW DPQQGEILLN DSPIASLNEA ALRQTISVVP 420
QRVHLFSATL RDNLLLASPG SSDEALSEIL RRVGLEKLLE DAGLNSWLGE GGRQLSGGEL 480
RRLAIARALL HDAPLVLLDE PTEGLDATTE SQILELLAEM MREKTVLMVT HRLRGLSRFQ 540
QIIVMDNGQI IEQGTHAELL ARQGRYYQFK QGL 573 
Gene Ontology
 GO:0016021; C:integral to membrane; IDA:EcoCyc.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IDA:EcoCyc.
 GO:0033228; P:cysteine export; IDA:EcoCyc.
 GO:0034775; P:glutathione transmembrane transport; IDA:EcoCyc.
 GO:0070453; P:regulation of heme biosynthetic process; IMP:EcoCyc. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR014223; ABC_CydC.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00664; ABC_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS