CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026192
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sprouty-related, EVH1 domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Spred2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
262RHAPVRGKYLDTTEDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 437 AA 
Protein Sequence
MTEETHPDDD SYIVRVKAVV MTRDDSSGGW FPQEGGGISR VGVCKVMHPE GNGRSGFLIH 60
GERQKDKLEV LIPVPAPTPS SETVASLWSP SFCKAVVLEC YVRKDLVYTK ANPTFHHWKV 120
DNRKFGLTFQ SPADARAFDR GVRKAIEDLI EGSTTSSSTL HNEAELGDDD VFTTATDSSS 180
NSSQKREPTT RTISSPTSCE HRKIYTLDPY PMDHYHPDQR LPRSYPQVTF PEDDEEIVRI 240
NPREKIWMTG YEDYRHAPVR GKYLDTTEDA DSYVRFAKGE VPKHEYTYPY VDSSDFGFGE 300
DPKGSVIKTQ PPRAKSRRRK ENGERSRCVY CRDMFNHEEN RRGHCQDAPD AVRTCIRRVS 360
CMWCADSMLY HCMSDPEGDY TDPCSCDTSD EKFCLRWMAL IALSFLAPCM CCYLPLRACH 420
RCGVMCRCCG GKHKAAA 437 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; IDA:MGI.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0000188; P:inactivation of MAPK activity; IMP:MGI.
 GO:0007275; P:multicellular organismal development; IEA:InterPro. 
Interpro
 IPR000697; EVH1.
 IPR023337; KBD.
 IPR011993; PH_like_dom.
 IPR007875; Sprouty. 
Pfam
 PF05210; Sprouty
 PF00568; WH1 
SMART
  
PROSITE
 PS51488; KBD
 PS51227; SPR
 PS50229; WH1 
PRINTS