UniProt Accession

 DTD2_MOUSE; Q8BHA3; Q9D363; Q9D4Q5 

Genbank Protein ID

 AK016300; AK018311; AK032228; AK042771; BC089589 

Genbank Nucleotide ID

 BAB30185.1; BAB31157.1; BAC27771.1; BAC31360.1; AAH89589.1 

Protein Name

 Probable D-tyrosyl-tRNA(Tyr) deacylase 2 

Protein Synonyms/Alias

 D-tyrosyl-tRNA deacylase 2 

Gene Name

 Dtd2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
59	ADTDLLPKMVNTLLN	ubiquitination	[1]
76	LSETETGKHVSILDL	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential). 

Sequence Annotation

 ACT_SITE 94 94 Nucleophile (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 168 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
 GO:0019478; P:D-amino acid catabolic process; IEA:InterPro. 

Interpro

 IPR023509; DTD-like_dom.
 IPR003732; DTyrtRNA_deacyls. 

Pfam

 PF02580; Tyr_Deacylase 

SMART

  

PROSITE

  

PRINTS