CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032636
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PHD-finger domain-containing protein, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_062330 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
793TSQESPEKKAAASQPacetylation[1]
794SQESPEKKAAASQPVacetylation[1]
1063AEQGSGGKLEATETPacetylation[1, 2]
1077PAADNAVKTEKKGDAacetylation[1, 2]
2776DEGGFSEKGEDRQREacetylation[1, 2]
3250RSGGLLFKRGGGGARacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3874 AA 
Protein Sequence
MGLPSAHADT VGSDASSAGS VDVASSSSQP ASSGAEKRGA HGRVEASNND GPSESPRLSP 60
RSPTHCSSLS SRVSACAMTP PLGCNPAQGG EGERSGGLSD SHPTECNNGA AATCAVEKNA 120
VPPVSPVERD APAPVPVSSL GSPPNRAQKT AASPLFGASL EHRASGKKRN GASPGESQQG 180
DSGQTGEAAE EGGASAVSKC TDAEGFPIPD PPRVAGAALL PSAAPAGPAR ALEAKLEETA 240
ARGRSVNRRR SGSPPSDVSP VNTVSAVSSL PAASASSAPY PSLPSSSVAS SSISSSAASA 300
APSQASLPGA SVPGNLLGNL AAWAASGARA PSSPAALLSA ALSRSLQPLS SPLVPSTPLL 360
VSPGGSYAGL SASAPRPSLS VAPATSSALL SASSLAPGGL AGPGATPPAV VAPSLVAALR 420
NLPSFGLQPL QPRFVSRASV DGAAPLASSP SSLAGAAASP THGAPSVNGG DIPNISRRRS 480
AGANAVPGTN QHSFSGQTPQ LASPFLPGNL LQAAALLSSS QNHVALLSSL ASSLPASTPL 540
APRYLRPQGL PAGSLSPVAL QRQGACSPSS SAGPQASALA SACPSTEALA PTGGDSAPAK 600
AAAGGACGDP LSVERGGSGQ PEDVLNAEKE GGDATGARAS QELGLEAREG DLKRRRPSDP 660
AVSQSLSSPT SFSRGSSSAR AAGSRASSAS GQKGENGLEA DEDAVCSVCV VGECEQHNNI 720
VFCDGCGCAV HQFCYGVMQI PEGPWFCSLC TWLRKKKGGA DAASRKKEDR ASTPSPLDSA 780
AASPETSQES PEKKAAASQP VDSASSSPSS ASASAASPAS SVLCKLCGQG GGAMRRGPEK 840
LWVHSCCVLY CRSGPQFRRT LQLDEPVDIR PSLSVARAMA WRCVVCRKRE GLPISCGFPG 900
CSNRLHVTCA RAAKCVCVIA SLWEGPVEGA GRERVWKAVF CPTHNDPVSI QAAKEFERER 960
AFAASPVPAS TLASLPAGGV SPVHAGVSPL QAAVAPVPAA GSPFSSPQAP GGVSEGERRL 1020
EEWAQQGRAL GSIPGGVEPV HVATSFGVAR ASAPQAEQGS GGKLEATETP AADNAVKTEK 1080
KGDAISGRRD EEANRQASTL GDAAQASLSS LSSSPTQSGS RAVGGGAGVR PADSRDTLGS 1140
APPLSRALQA RQAPASGLAL EETLNALQRG VPPRAGAPSL LSPGVSALRL LPGATAPAGA 1200
PAASAGAFQQ TPLSLGSVFP FGAASGVQGA QGLSPEVLQK QLLLQALAGG TGPARQGQQA 1260
QKPQGFALGS GLTSPAIAPF LDALVNPANQ KKDDAQRAHP ALASTWGQPL LGNFAGQGAN 1320
FLAPSGLPAS PAAPGSNLLS QYAAPASVFR GQAVVSPSVC GLLCPNVAGV GGAASTLGGA 1380
APGLGGGAAG LGGLQAGAAV AGVRGGVGPQ FALLPQQLLS AQTRGTQQAV DLARANCLLP 1440
GSSFPLRFPD AGPSGGTSGR EGAESAVAAG PARPAGGARQ ERREAGDASS SPGGLCVSGA 1500
PPPGSLGSSS KAEAPTGHTV GAGGPAQADG EAQGPAGFAE TSEAPLALSP SSPRPSPLLR 1560
SSGALRSAGK RGGRGRSSHR MWFSSSRKSQ PGVLGSQARG GMLGSKNGLL GGAFSTQLLE 1620
GGVGADLLVD GALGGTGGSH GVHTPGTTRG SRVQWGRFDL LFRRVPVGPF ATNVLETLKT 1680
SQEKRVAIEE ARVIEKILTS PCLCPEAESL TEPPLEDREV VEELLELYVH QVDEALRRAR 1740
ERKKRRRRRA REKREEQERC EGRTAEKEEG DAEALTPNKK RMSSESPQNR DGDADASETQ 1800
DVGDHVPDRE GDPGENIQDI KVRLHSSVDT GDSSSGSPSV VLPPEKACEA TTAACALPKE 1860
ESGGTPQQAT DAGESESPAG AAIADSSSVC TPEAAESMKR PSDAKKRERD QAKAADKDDE 1920
EVCLPFTALV DFGPVAAWIL FEAVPGEPQS AEECEVLERL CESGYLPGSP SFALRKFHSD 1980
PAVSSPGLGA VGFPPLSPSL GDSSLPPAAG DRRLLAGAAR GGAASAGDLG AGRAASLFSL 2040
PGDSVDAPAS PLAFPGERQG RRSPSQTLGA AAPSPEAGGM LDEGGWCTST AEEAEVVKEA 2100
RAGATKAVNV FGREKENGRV HADREDSADG DSGSEVETEG AKPGLPYRLV VKAFKTLSFY 2160
QLTYCRRRLQ QVFLRPHRHP LYRQLLQVEA EQRKRREREG QRAGEHVDQE EGEDMQKVFP 2220
LFQLSSTLAD PKLGSAEKLR NKQEKSVGLA SKKVFSKETA ESRETQVRQP ETRERRVLVS 2280
EAADRIGSCT PSELGQTRED ETKDAASPGL PPKRVENATG SGSPSLLGPV RSEATNDACT 2340
HSSPLTPNNV SATGEIERTR NEDMASDERK NMSTAAATEP VLSASPLGLL PPPRGLRPPL 2400
RPDGKVQSLQ TPESEVQPGD SGASIVTVGG HRWFVKPWGW HESPYASLVQ GGDDFVGVQC 2460
AQFLQVRSRQ KSTADARGVV GCTDARSQLG AASFCSSPLH SVLVRSWNPF SSVVCGHCLL 2520
CVSPSRRSSV GTSRHLSPRA FCPFADLQVS TVLSRDLRRL KLHLLQSVLE ENRQPLKVVE 2580
RPQSADRLLA RYASMHRWSQ LRHYLCEGVK DVPLPASPPT PAPGAPAAAP GSSAAGRRGA 2640
AREPPGPVVE APKPASASAV CPAVPPHLRN LCQSPEQEAQ LLKQRRQLCE ARALRVPSFP 2700
DPRTCFLLAQ QEKYQRQLGC LSDSVAACAA VAGWGLGSMG LASCSAAELE RRLLLAFPAS 2760
PFSGKREEDE GGFSEKGEDR QRETRNVCFA DFVVDLVAGS PKAGGAKDEK LADLLEECNA 2820
NFSLFLHDEA EEESRRAQNT QPVLLASGVE KARPAVREDD RGDPEAAARG KVDENTKDAT 2880
EKKDAQATKE EAPEQNESQE KKEALEHPQS QRTTETQPRH ASPLPELAAP ASTSPQSLEG 2940
GGAADTVRGP PSAEPSGAAA SPAAAAVSVS PASPLPARTA AAAAPVAATA GSVLDALVGA 3000
AGAASCCVCW WSERSNLNPI LSCVRCLVHV HKNCYGVGKM GEAVEGDDWI CRRCELEKKG 3060
LGTQWLVAFE PMKVRCQVCG TGGGALKQTT DGAWVHLFCV LWLLPEVSCG DFASLEPWNL 3120
EGVVAWRREA RCGLCDQPGG ICVRCASVGC EVCFHPMCAW LAGLHCEAES LRGLFLPFRG 3180
AVDRCFPRLV IKALCYKHSP EFLPDGRRFH FASRSSAVQG SLRMRRYVTR DHRPDLFNAN 3240
DRRSGGLLFK RGGGGARRGN ASAGSAFGAQ RARTQAAVAA SLPKTEFPAL PPPAPLPPTS 3300
PGTGADRQPA TPPAPDAQPL APIAVEGDVP TEAPHDGDSK TAPSKLEALA SPAASLESSS 3360
VVSSSEFSSS SASSSSASSS SASSSSASSS SASSSSASSS SASSSSASSS SASSSSASSS 3420
SASSSAASSS SASSSAASCE SSPVVSCPEL SSSSSASSSA AASCESSSSS ASSSAAASCE 3480
SSSSSASSSA AASCESSSSS ASSSAAASCE SSSSSVSCPE PPSSSAASAV TSSVSPGGVD 3540
EKDVCSDAPG NSRASPEAAA PVEKGTEETS PLVCSPVSPA AVSGRGPTGS PAGEKGSAES 3600
VPRTEESAGA ADLTRAVLEE MDLYDDHSCA VCLLPRITCT SSNPFFHCQR CGLCVHRQCY 3660
GIRKEHLPLH LRPDLLRKIE GRKMRRLSAP SGGTMETRCE EADGSGGDGG GDGGDGAGQG 3720
AEGTGPAAEV GSGQADGSGM EDAEERCSSS FSRGASAELQ AAPQRKTAGE TTSGDDLSEE 3780
VEPERRDAAS PSGADAREAD DSERMKKRTR EDSERETSCV ETDEEENVCQ YKPRPFLCEA 3840
CTWLPPTEKV SKRGGREKQK EEEGMYCRQR RTLH 3874 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00249; PHD 
PROSITE
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS