CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011708
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RUN domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Rundc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
497YVESPARKLSQSFALubiquitination[1]
596LSRLSSLKFSLPVDLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May play a role as p53/TP53 inhibitor and thus may have oncogenic activity (By similarity). 
Sequence Annotation
 DOMAIN 423 604 RUN.
 MOD_RES 73 73 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 615 AA 
Protein Sequence
MATVEVATEL GTVVTAVGPK AKDEEEEEEE EESLPPCETV RWAPVGAVAE AGPGAATFSE 60
AAAAEEPGAA PGSPSDATVR TLRRLEAERR QLDSALLALS SHFAQVQFRL RQVVRGAPAE 120
QQRLLRELED FAFRGCPHVL GYEGLADPCG GDESDVLPGD RPRVRGEDQS EQEKRERLET 180
QREKQKELIL QLKTQLDDLE TFAYQEGSYD SLPQSVVLER QRVIIDELIK KLDMNLNEDI 240
SSLSTEELRQ RVDAAVAQIV NPVRVKEQLV EQLKTQIRDL EMFISFIQDE VGSPLQTGGH 300
CECQASGKVG IGSTRVGGST LPPGPGKAKA EDAKRARETG LHLMRRALAV LQIFTVSQLG 360
CATGQIPQTL WQRSQADRDY SHLLKRLEVS VDRVKQLALR HQPHDHVITS ANLQDLSLGG 420
KDELTTVVRK ELTVAVRDLL AHGLYASSSG MSLVMAPLAC LLPVFSSAPE TMHPWELFVK 480
YYHAKNGRAY VESPARKLSQ SFALPIMGDT AVTPKQSLLT AIHLVLTEHD PFKRSADSEL 540
KALVCMALNE QRLVSWVNLI CKSGSLIEPH YQPWSYMAHT GFESALNLLS RLSSLKFSLP 600
VDLAVRQLKN IKDAF 615 
Gene Ontology
  
Interpro
 IPR004012; Run. 
Pfam
 PF02759; RUN 
SMART
 SM00593; RUN 
PROSITE
 PS50826; RUN 
PRINTS