CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027297
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA gyrase subunit B 
Protein Synonyms/Alias
  
Gene Name
 LA_4194 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Leptospira interrogans serogroup Icterohaemorrhagiae serovar La 
NCBI Taxa ID
 189518 
Lysine Modification
Position
Peptide
Type
References
98KSIPEKDKMSKLIVQmethylation[1]
101PEKDKMSKLIVQLSSmethylation[1]
Reference
 [1] High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans.
 Cao XJ, Dai J, Xu H, Nie S, Chang X, Hu BY, Sheng QH, Wang LS, Ning ZB, Li YX, Guo XK, Zhao GP, Zeng R.
 Cell Res. 2010 Feb;20(2):197-210. [PMID: 19918266] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Isomerase; Nucleotide-binding; Reference proteome; Topoisomerase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MSTDKTKVKE KSSQERNFKK LSNVEHVRMR TGMWLGQNSA STFEQHFFRK NNEGKYEIVH 60
EELEDVPAKL KCLDEACMNA VDEYRKNQKD KSIPEKDKMS KLIVQLSSDR KCVTIADNGR 120
GIPATNAEGV YLHLMYGENF DDHVKQDHVA GQNGVGISLV RMVSNYFKVK TVNNGSSFKK 180
LFTVHDDVKK QIRSYKLSKE DTERVFLYFD EHGKFTDCNL LTKDQIDKLS PLLKKTNMQE 240
LIEKASKEDH GTSVEFELNP KYFNNLDISF NVDLMKQYLQ DIAMTNPGLE VQFVFKGKKE 300
KYKFKKGLDE IFSHSDLVYY KMDYVAPGSA SQLHLETYLV IGQNKNLTWV NSIFAPQGGS 360
AIEYLENRIC DEVRKKSQIV ALEKKLKTSS TRNDVRNCFH MYVNARLLNP RFKSQDKSYL 420
INDLNEDIRN AVDKHLDKFI KKTGLLEEIK LQMEKRTQLK AFEDAQKGLK KASRMNIPKL 480
MPPTGKQGDP GRVLFVAEGD SAIAGLRPAR NPKLHGLFPL RGKPLNCKGL SIAKAIANEE 540
LKNIVAIVGL PLDQKVKSLD ELNYEKVSII TDADFDGYAI RSLMLSFFYE YWPELFELGF 600
IHISSAPLYE VDVKFGDKKK ETIFCIDDKD YEDLIKRVEK GGGEITRKKR NKGLGETGKE 660
AMKFAVEECM TKITIGNKKE ASKIQSLWFH KDYAEQRRDA ISEYAMSVIE D 711 
Gene Ontology
 GO:0009295; C:nucleoid; IBA:RefGenome.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IBA:RefGenome.
 GO:0007059; P:chromosome segregation; IBA:RefGenome.
 GO:0006265; P:DNA topological change; IBA:RefGenome.
 GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome. 
Interpro
 IPR003594; HATPase_ATP-bd.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
 IPR001241; Topo_IIA.
 IPR013506; Topo_IIA_bsu_dom2.
 IPR013759; Topo_IIA_cen_dom.
 IPR013760; Topo_IIA_like_dom.
 IPR018522; TopoIIA_CS.
 IPR006171; Toprim_domain. 
Pfam
 PF00204; DNA_gyraseB
 PF02518; HATPase_c
 PF01751; Toprim 
SMART
 SM00387; HATPase_c
 SM00433; TOP2c 
PROSITE
 PS00177; TOPOISOMERASE_II 
PRINTS
 PR00418; TPI2FAMILY.