CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030711
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AN1-type zinc finger protein 2B 
Protein Synonyms/Alias
 cDNA FLJ60439, highly similar to AN1-type zinc finger protein 2B 
Gene Name
 ZFAND2B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
24RLDFLPLKCDACSGIubiquitination[1]
92RSDPAQQKRKIFTNKubiquitination[2]
94DPAQQKRKIFTNKCEubiquitination[1]
99KRKIFTNKCERAGCRubiquitination[1, 3, 4]
112CRQREMMKLTCERCSubiquitination[1, 4]
125CSRNFCIKHRHPLDHubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 225 AA 
Protein Sequence
MEFPDLGAHC SEPSCQRLDF LPLKCDACSG IFCADHVAYA QHHCGSAYQK DIQVPVCPLC 60
NVPVPVARGE PPDRAVGEHI DRDCRSDPAQ QKRKIFTNKC ERAGCRQREM MKLTCERCSR 120
NFCIKHRHPL DHDCSGEGHP TSRAGLAAIS RAQAVASTST VPSPSQTMPS CTSPSRATTR 180
SPSWTAPPVI ALQNGLVSWA EVGWTETNTQ RVKSKDAGLL SPFVE 225 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR000058; Znf_AN1. 
Pfam
 PF01428; zf-AN1 
SMART
 SM00154; ZnF_AN1 
PROSITE
 PS51039; ZF_AN1 
PRINTS