CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024288
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HEAT repeat-containing protein 6 
Protein Synonyms/Alias
  
Gene Name
 Heatr6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
640TKVWNHIKPYIRHKDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 REPEAT 230 269 HEAT 1.
 REPEAT 524 562 HEAT 2.
 REPEAT 586 624 HEAT 3.
 REPEAT 630 667 HEAT 4.
 MOD_RES 714 714 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1252 AA 
Protein Sequence
MSALPGSKLS ERVRTVGWQI SRPYFCHFFP IRITAPPATC SANKGFPELE HARPCPKRCP 60
GSISQAIHVG KMAAVQVAAS LPCEQPREAP RELSLEQNNG FRRLSARLRA LQPDDSTVSR 120
MEIHLLFDQL ISENYCEGGG VAPEDVSALL VRACQLVPLN QNHLVSKVSQ LIHRLLNRLQ 180
VIVDEQNLDF LLTYTISAIQ QCSPWTHMEI LQALAALVYC NGSKCQKHLP DLLGKSGLLM 240
KLSDVTHSDP EVRRAAVHCM ANLCLSVPGQ PYLEESYQLV CFQAFLTILQ SPKSSDMDDI 300
TFCMLLQNAL KGIQSLLNGG KMRLTQTEHL GALLAVLKKA MFHGLPGLNI EMPAVLYPTP 360
LPQYDGRSPV KPQQPESSAA RPSANKKKKY KVKPKKTQQG EKAEEEEPYG EVDAAPGLSM 420
DQANTCVESA WCSSPWGSQG LPVDGGRATG REQVSSPFTI SSWKRVSSSE SDYSDAEGGM 480
QGKMRSYQAK VRQGALACFL STIKSIEKKV LYGYWSAFVP DTPELGSPQS VSLMTLTLKD 540
PSPKTRACAL QVLSAILEGS KQFLSVAEDT SDHKRAFTPF SVTIASSIRE LHRCLLLALV 600
AESSSQTLTQ IIKCLANLVS NAPYNRLKLS LLTKVWNHIK PYIRHKDVNV RVSSLTLLGA 660
VVSTHAPLPE VQLLLQQPCS SGRSSSSATP HLSTPDGWKA LPAGPSLEEA SLSSPKGTAE 720
PCWLIRLCIS TVVLPKEDSC SGSDAGSALG STYEPSPMRL EALQVLAHLA RGYFSMAQLY 780
LMELGEVICK CMCEANPSIQ LHGVKLLEEL GTGLIQQYKP DSSTAPEQRV PVHMVAMFWT 840
AMLNGPLPRA LQSTEHPTLQ ASACDALSSI LPEAFSSLPN DKQILCITML LGLNDSKNHL 900
VKAATSRALG VYVLFPCLRQ DVIFVADTAN AILMSLQDKS LNVRAKAAWS LGNLTDTLIV 960
NMDTPDPSFQ DEFSGLLLLK MLQSAIQAST DKDKVKSNAV RALGNLLHFL QPSHIERPRF 1020
AEIIEESIQA LISTVVNEAA MKVRWNACYA MGNVFKNPAL PLGTAPWTSQ AYKALTSVVM 1080
SCKNFKVRIR SAAALSVPGR RAQYGSLEQF SQIWSALVTA LQRSEDTTDF LEFKYCASLR 1140
THVCQALLHL LGLASASDLP CIQETLTVNG DMIRSYILQF LKSGAGGDDP GAVHSPQERN 1200
QMVRVALRHI HSVQALAGDT AKGAIVGFLE DILTVHCDSS GERAVLRGSL DQ 1252 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR025283; DUF4042. 
Pfam
 PF13251; DUF4042 
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS