CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038750
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Platelet-activating factor acetylhydrolase 2, cytoplasmic 
Protein Synonyms/Alias
  
Gene Name
 Pafah2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
199RRIKEGEKEFHVRNPacetylation[1, 2]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 415 AA 
Protein Sequence
MPEIIEDLSW PANSRAPGFG PAGDEMGAGQ SVCFPPISGP HHIGCTDVME GHSLEGSLFR 60
LFYPCQASEK CEQPLWIPRY EYSMGLADYL QYNKRWVGLL FNVGIGSCRL PVSWNGPFKA 120
KESGYPLIIL SHGLGGFRAS YSAFCMELAS RGFVVAAVEH RDQSAAATYF CKPTSQESSP 180
AESLEEEWLP FRRIKEGEKE FHVRNPQVHQ RVKECVRVLR ILQDASAGKT VVNVFPGGLD 240
LMTLKGSIDR NRVAVMGHSF GGATAVLALT QEVQFRCAIA LDAWMFPLER DFYPKARGPV 300
FFINVEKFQT VESVNLMKKI CAQHEQSRIV TVLGAVHRSQ TDFAFVTGNL IAKFFSSNSR 360
GTLDPYESQE VMVRAILAFL QKHLDLKEDY DQWSSFIEGV GPSLIQGAPH YLSSL 415 
Gene Ontology
 GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:InterPro.
 GO:0016042; P:lipid catabolic process; IEA:InterPro. 
Interpro
 IPR016715; Ac_Ohase_PAF.
 IPR005065; PAF_acetylhydro. 
Pfam
 PF03403; PAF-AH_p_II 
SMART
  
PROSITE
  
PRINTS