UniProt Accession

 DYL2_BOVIN; Q3MHR3 

Genbank Protein ID

 BC105140 

Genbank Nucleotide ID

 AAI05141.1 

Protein Name

 Dynein light chain 2, cytoplasmic 

Protein Synonyms/Alias

  

Gene Name

 DYNLL2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Bos taurus (Bovine) 

NCBI Taxa ID

 9913 

Lysine Modification

Position	Peptide	Type	References
36	MEKYNIEKDIAAYIK	ubiquitination	[1]
44	DIAAYIKKEFDKKYN	ubiquitination	[1]
49	IKKEFDKKYNPTWHC	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May be involved in some aspects of dynein-related intracellular transport and motility. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Cytoskeleton; Dynein; Microtubule; Motor protein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 89 AA 

Protein Sequence

Gene Ontology

 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0016459; C:myosin complex; IEA:Compara.
 GO:0003774; F:motor activity; IEA:UniProtKB-KW.
 GO:0007017; P:microtubule-based process; IEA:InterPro.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR019763; Dynein_light_1/2_CS.
 IPR001372; Dynein_light_chain_typ-1/2. 

Pfam

 PF01221; Dynein_light 

SMART

  

PROSITE

 PS01239; DYNEIN_LIGHT_1 

PRINTS