CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 
Protein Synonyms/Alias
  
Gene Name
 Ndufaf6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
161RIIDEREKNLDDKAYacetylation[1]
166REKNLDDKAYRSMQEacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1 (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 333 AA 
Protein Sequence
MATSMLGSVR GPRPFGLANL FHRQPPRDAW ERVRRLPGPS AVRRSVAAAS GPGIPGSHLY 60
CLELLRKRDY ESYLCSLLFP AECQRSASAL RAFNVELAQV KDSVSEKTIG LMRMQFWKKA 120
VEDMYCDNPP HQPVAIELWK AVKKHNLTKR WLMRIIDERE KNLDDKAYRS MQELENYAEN 180
TQGSLLYLTL EVLGVKDLHA DHAASHIGKA QGIVTCLRAT PYHSSRRQVF LPMDVCVQHG 240
VSQEDFLRRN QDKNVRDVVY DIASQAHLHL KHARSFHRSV PAEAFPAFLQ TVSLEDYLKK 300
IQRVDFDIFH PSLQQKNMLL PLSLYIQSWR KRY 333 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016740; F:transferase activity; IEA:InterPro.
 GO:0009058; P:biosynthetic process; IEA:InterPro.
 GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Compara. 
Interpro
 IPR002060; Squ/phyt_synthse.
 IPR008949; Terpenoid_synth. 
Pfam
 PF00494; SQS_PSY 
SMART
  
PROSITE
  
PRINTS