UniProt Accession

 RAB6B_MOUSE; P61294 

Genbank Protein ID

 AK035893; BC060618 

Genbank Nucleotide ID

 BAC29230.1; AAH60618.1 

Protein Name

 Ras-related protein Rab-6B 

Protein Synonyms/Alias

  

Gene Name

 Rab6b 

Gene Synonyms/Alias

 D9Bwg0185e 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
15	GNPLRKFKLVFLGEQ	ubiquitination	[1]
26	LGEQSVGKTSLITRF	ubiquitination	[1]
127	IIMLVGNKTDLADKR	ubiquitination	[1]
133	NKTDLADKRQITIEE	ubiquitination	[1]
164	AKTGYNVKQLFRRVA	ubiquitination	[1]
183	GMENVQEKSKEGMID	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (By similarity). 

Sequence Annotation

 NP_BIND 20 27 GTP (By similarity).
 NP_BIND 68 72 GTP (By similarity).
 NP_BIND 126 129 GTP (By similarity).
 MOTIF 42 50 Effector region (By similarity).
 BINDING 45 45 GTP (By similarity).
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 208 208 Cysteine methyl ester (By similarity).
 LIPID 206 206 S-geranylgeranyl cysteine (By
 LIPID 208 208 S-geranylgeranyl cysteine (By  

Keyword

 Acetylation; Complete proteome; Cytoplasmic vesicle; ER-Golgi transport; Golgi apparatus; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.