CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016906
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cell division cycle protein 123 homolog 
Protein Synonyms/Alias
  
Gene Name
 Cdc123 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
168EYELVLRKWCELIPGacetylation[1]
168EYELVLRKWCELIPGubiquitination[2]
321STGEDAHKLIDFLKLubiquitination[2]
327HKLIDFLKLKRNEQEubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Required for S phase entry of the cell cycle (By similarity). 
Sequence Annotation
 MOD_RES 60 60 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Cell cycle; Cell division; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 336 AA 
Protein Sequence
MKKEHVSHCQ FSAWYPLFRS LTIKSVILPL PQNVKDYLLD DGTLVVSGRE DPPTCSQSDS 60
GNEAEETQWS DDESTATLTA PEFPEFNTQV QEAINSLGGS VFPKLNWSAP RDAYWIAMNS 120
SLKCKTLSDI FLLFKSSDFI THDFTQPFIH CTDDSPDPCI EYELVLRKWC ELIPGAEFRC 180
FVKENKLIGI SQRDYTQYYD HISKQKEEIC RCIQDFFKEH LQYKFLDEDF VFDIYRDSRG 240
KVWLIDFNPF GEVTDSLLFT WEELTSENNL RGEVTEGDAQ EQDSPAFRCT NSEVTVQPSP 300
YLSFGLPKDF VDLSTGEDAH KLIDFLKLKR NEQEDD 336 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW. 
Interpro
 IPR016525; Cell_div_Cdc123.
 IPR009772; D123. 
Pfam
 PF07065; D123 
SMART
  
PROSITE
  
PRINTS