CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016568
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Golgi pH regulator 
Protein Synonyms/Alias
 Protein GPR89 
Gene Name
 Gpr89a 
Gene Synonyms/Alias
 Gphr; Gpr89 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
272TADLYATKERIEYSKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (By similarity). 
Sequence Annotation
 CARBOHYD 180 180 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Golgi apparatus; Ion channel; Ion transport; Membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 455 AA 
Protein Sequence
MSFLIDSSIM ITSQILFFGF GWLFFMRQLF KDYEVRQYVV QVIFSVTFAF SCTMFELIIF 60
EILGVLNSSS RYFHWKLNLC VILLILVFMV PFYIGYFIVS NIQLLHKQRL LFSCLLWLTF 120
MYFFWKLGDP FPILSPKHGI LSIEQLISRV GVIGVTLMAL LSGFGAVNCP YTYMSYFLRN 180
VTDTDILALE RRLLQTMDMI ISKKKRMAVA RRTMFQRGDV QNKPSGLWGM LKSVTASAPG 240
SENLTLIQQE VDALEELSRQ LFLETADLYA TKERIEYSKT FKGKYFNFLG YFFSIYCVWK 300
IFMATINIVL DRVGKTDPVT RGIEITVNYL GIQFDVKFWS QHISFILVGI IIVTSIRGLL 360
ITLTKFFYAI SSSKSSNVIV LLLAQIMGMY FVSSVLLIRM SMPPEYRTII TEVLGELQFN 420
FYHRWFDVIF LVSALSSILF LYLAHKQAPE KHMAP 455 
Gene Ontology
 GO:0032580; C:Golgi cisterna membrane; ISS:UniProtKB.
 GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0008308; F:voltage-gated anion channel activity; ISS:UniProtKB.
 GO:0051452; P:intracellular pH reduction; ISS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0043588; P:skin development; IMP:MGI. 
Interpro
 IPR025969; ABA_GPCR_dom.
 IPR022535; Golgi_pH-regulator_cons_dom.
 IPR015672; GPCR89-rel. 
Pfam
 PF12430; ABA_GPCR
 PF12537; DUF3735 
SMART
  
PROSITE
  
PRINTS