| Tag | Content |
|---|
| CPLM ID | CPLM-008573 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mannosyl-oligosaccharide glucosidase |
Protein Synonyms/Alias | Processing A-glucosidase I; Glucosidase I |
Gene Name | CWH41 |
Gene Synonyms/Alias | GLS1; YGL027C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 542 | GLLTEYAKKIYPKLL | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor highly specifically. Seems to play a role in beta-1,6-glucan synthesis. |
Sequence Annotation | CARBOHYD 42 42 N-linked (GlcNAc...) (Potential).
CARBOHYD 122 122 N-linked (GlcNAc...) (Potential).
CARBOHYD 135 135 N-linked (GlcNAc...) (Potential).
CARBOHYD 787 787 N-linked (GlcNAc...) (Potential). |
Keyword | 3D-structure; Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosidase; Hydrolase; Membrane; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 833 AA |
Protein Sequence | MLISKSKMFK TFWILTSIVL LASATVDISK LQEFEEYQKF TNESLLWAPY RSNCYFGMRP 60
RYVHESPLIM GIMWFNSLSQ DGLHSLRHFA TPQDKLQKYG WEVYDPRIGG KEVFIDEKNN 120
LNLTVYFVKS KNGENWSVRV QGEPLDPKRP STASVVLYFS QNGGEIDGKS SLAMIGHDGP 180
NDMKFFGYSK ELGEYHLTVK DNFGHYFKNP EYETMEVAPG SDCSKTSHLS LQIPDKEVWK 240
ARDVFQSLVS DSIRDILEKE ETKQRPADLI PSVLTIRNLY NFNPGNFHYI QKTFDLTKKD 300
GFQFDITYNK LGTTQSISTR EQVTELITWS LNEINARFDK QFSFGEGPDS IESVEVKRRF 360
ALETLSNLLG GIGYFYGNQL IDRETEFDES QFTEIKLLNA KEEGPFELFT SVPSRGFFPR 420
GFYWDEGFHL LQIMEYDFDL AFEILASWFE MIEDDSGWIA REIILGNEAR SKVPQEFQVQ 480
NPNIANPPTL LLAFSEMLSR AIENIGDFNS DSYHQVMFNS RTAKFMTNNL EANPGLLTEY 540
AKKIYPKLLK HYNWFRKSQT GLIDEYEEIL EDEGIWDKIH KNEVYRWVGR TFTHCLPSGM 600
DDYPRAQPPD VAELNVDALA WVGVMTRSMK QIAHVLKLTQ DEQRYAQIEQ EVVENLDLLH 660
WSENDNCYCD ISIDPEDDEI REFVCHEGYV SVLPFALKLI PKNSPKLEKV VALMSDPEKI 720
FSDYGLLSLS RQDDYFGKDE NYWRGPIWMN INYLCLDAMR YYYPEVILDV AGEASNAKKL 780
YQSLKINLSN NIYKVWEEQG YCYENYSPID GHGTGAEHFT GWTALVVNIL GRF 833 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0004573; F:mannosyl-oligosaccharide glucosidase activity; IDA:SGD. GO:0009272; P:fungal-type cell wall biogenesis; IMP:SGD. GO:0009311; P:oligosaccharide metabolic process; IEA:InterPro. GO:0006487; P:protein N-linked glycosylation; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |