| Tag | Content |
|---|
| CPLM ID | CPLM-006740 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative prophage CPS-53 integrase |
Protein Synonyms/Alias | |
Gene Name | intS |
Gene Synonyms/Alias | intC; yfdB; b2349; JW2345 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 54 | EKILTVGKYPLMTLQ | acetylation | [1] | | 368 | NHAQYLDKRREMMQW | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. |
Sequence Annotation | ACT_SITE 360 360 O-(3'-phospho-DNA)-tyrosine intermediate |
Keyword | 3D-structure; Complete proteome; DNA integration; DNA recombination; Reference proteome; Viral genome integration; Virus entry into host cell. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 385 AA |
Protein Sequence | MLTVKQIEAA KPKEKPYRLL DGNGLYLYVP VSGKKVWQLR YKIDGKEKIL TVGKYPLMTL 60
QEARDKAWTA RKDISVGIDP VKAKKASSNN NSFSAIYKEW YEHKKQVWSV GYATELAKMF 120
DDDILPIIGG LEIQDIEPMQ LLEVIRRFED RGAMERANKA RRRCGEVFRY AIVTGRAKYN 180
PAPDLADAMK GYRKKNFPFL PADQIPAFNK ALATFSGSIV SLIATKVLRY TALRTKELRS 240
MLWKNVDFEN RIITIDASVM KGRKIHVVPM SDQVVELLTT LSSITKPVSE FVFAGRNDKK 300
KPICENAVLL VIKQIGYEGL ESGHGFRHEF STIMNEHEWP ADAIEVQLAH ANGGSVRGIY 360
NHAQYLDKRR EMMQWWADWL DEKVE 385 |
Gene Ontology | GO:0003677; F:DNA binding; IEA:InterPro. GO:0015074; P:DNA integration; IEA:UniProtKB-KW. GO:0006310; P:DNA recombination; IEA:UniProtKB-KW. GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW. GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |