CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003218
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cold shock-like protein CspC 
Protein Synonyms/Alias
 CSP-C 
Gene Name
 cspC 
Gene Synonyms/Alias
 msmB; b1823; JW1812 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
5***MAKIKGQVKWFNacetylation[1]
9AKIKGQVKWFNESKGacetylation[1]
9AKIKGQVKWFNESKGpupylation[2]
15VKWFNESKGFGFITPacetylation[1]
27ITPADGSKDVFVHFSacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli.
 Cerda-Maira FA, McAllister F, Bode NJ, Burns KE, Gygi SP, Darwin KH.
 EMBO Rep. 2011 Jul 8;12(8):863-70. [PMID: 21738222
Functional Description
  
Sequence Annotation
 DOMAIN 6 66 CSD.  
Keyword
 Activator; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 69 AA 
Protein Sequence
MAKIKGQVKW FNESKGFGFI TPADGSKDVF VHFSAIQGNG FKTLAEGQNV EFEIQDGQKG 60
PAAVNVTAI 69 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016020; C:membrane; IDA:UniProtKB.
 GO:0003723; F:RNA binding; IDA:EcoliWiki.
 GO:0001072; F:RNA binding transcription antitermination factor activity; IDA:EcoliWiki.
 GO:0003697; F:single-stranded DNA binding; IDA:EcoliWiki.
 GO:0060567; P:negative regulation of DNA-dependent transcription, termination; IDA:EcoliWiki.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR019844; Cold-shock_CS.
 IPR012156; Cold_shock_CspA.
 IPR011129; Cold_shock_prot.
 IPR002059; CSP_DNA-bd.
 IPR012340; NA-bd_OB-fold. 
Pfam
 PF00313; CSD 
SMART
 SM00357; CSP 
PROSITE
 PS00352; COLD_SHOCK 
PRINTS
 PR00050; COLDSHOCK.