CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026549
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Minichromosome maintenance deficient 7 (S. cerevisiae) 
Protein Synonyms/Alias
 Minichromosome maintenance deficient 7 (S. cerevisiae), isoform CRA_b; Protein Mcm7 
Gene Name
 Mcm7 
Gene Synonyms/Alias
 rCG_55961 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
4****MALKDYAIEKEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; DNA replication; DNA-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 719 AA 
Protein Sequence
MALKDYAIEK EKVKKFLQEF YYDDELGKKQ FKYGTQLVHL AHREQVALYV DLDDVAEDDP 60
ELVDSICENA KRYSRLFADV VQELLPEYKE KEVVNKDVLD VYIEHRLMME QRSRDPGAVR 120
NPQNQYPSEL MRRFELYFQG PSSSKPRVIR EVRADSVGKL LTVRGIVTRV SEVKPRMVVA 180
TYTCDQCGAE TYQPIQSPTF MPLIMCPSQE CQTNRSGGRL YLQTRGSKFI KFQEMKIQEH 240
SDQVPVGNIP RSITVVLEGE NTRIAQPGDH VSVTGIFLPV LRTGFQQMAQ GLLSETYLEA 300
HRVVKMTKSE DDVSGAGELS AEELKQIAEE DFYEKLAASI APEIYGHEDV KKALLLLLVG 360
GVDQSPQGMK IRGNIHICLM GDPGVAKSQL LSYIDRLAPR SQYTTGRGSS GVGLTAAVLR 420
DSVSGELTLE GGALVLADQG VCCIDEFDKM AEADRTAIHE VMEQQTISIA KAGILTTLNA 480
RCSILAAANP AYGRYNPRRS LEQNIQLPAA LLSRFDLLWL IQDRPDRDND LRLAQHITYV 540
HQHSRQPPAQ FEPLDMKLMR RYIAMCRERQ PTVPDSLADY ITAAYVEMRR EARASKDATY 600
TSARTLLAIL RLSTALARLR MVDIVEKEDV NEAIRLMEMS KDSLLGEKGQ TARTQRPADV 660
IFATVRELVS GGRSVRFSEA EQRCISRGFT PAQFQAALDE YEELNVWQVN TSRTRITFV 719 
Gene Ontology
 GO:0005829; C:cytosol; IDA:RGD.
 GO:0042555; C:MCM complex; IEA:Compara.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0005524; F:ATP binding; TAS:RGD.
 GO:0004003; F:ATP-dependent DNA helicase activity; IEA:Compara.
 GO:0003677; F:DNA binding; TAS:RGD.
 GO:0008094; F:DNA-dependent ATPase activity; TAS:RGD.
 GO:0003697; F:single-stranded DNA binding; IEA:Compara.
 GO:0008283; P:cell proliferation; TAS:RGD.
 GO:0071364; P:cellular response to epidermal growth factor stimulus; IEP:RGD.
 GO:0006260; P:DNA replication; TAS:RGD.
 GO:0006270; P:DNA replication initiation; IEA:InterPro.
 GO:0006268; P:DNA unwinding involved in replication; IEA:Compara.
 GO:0042325; P:regulation of phosphorylation; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; TAS:RGD.
 GO:0006974; P:response to DNA damage stimulus; IEA:Compara.
 GO:0042493; P:response to drug; IEP:RGD. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR008050; MCM7.
 IPR018525; MCM_CS.
 IPR001208; MCM_DNA-dep_ATPase.
 IPR012340; NA-bd_OB-fold.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00493; MCM 
SMART
 SM00382; AAA
 SM00350; MCM 
PROSITE
 PS00847; MCM_1
 PS50051; MCM_2 
PRINTS
 PR01657; MCMFAMILY.
 PR01663; MCMPROTEIN7.