| Tag | Content |
|---|
| CPLM ID | CPLM-011344 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Echinoderm microtubule-associated protein-like 5 |
Protein Synonyms/Alias | EMAP-5 |
Gene Name | EML5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 951 | AALAPGSKGLLLEDN | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). |
Sequence Annotation | REPEAT 59 100 WD 1.
REPEAT 104 145 WD 2.
REPEAT 148 187 WD 3.
REPEAT 195 233 WD 4.
REPEAT 235 273 WD 5.
REPEAT 280 321 WD 6.
REPEAT 323 362 WD 7.
REPEAT 406 445 WD 8.
REPEAT 449 488 WD 9.
REPEAT 561 601 WD 10.
REPEAT 725 766 WD 11.
REPEAT 770 811 WD 12.
REPEAT 814 853 WD 13.
REPEAT 861 900 WD 14.
REPEAT 901 940 WD 15.
REPEAT 996 1035 WD 16.
REPEAT 1038 1077 WD 17.
REPEAT 1080 1120 WD 18.
REPEAT 1236 1276 WD 19.
REPEAT 1412 1463 WD 20.
REPEAT 1467 1508 WD 21.
REPEAT 1511 1550 WD 22.
REPEAT 1560 1598 WD 23.
REPEAT 1600 1646 WD 24.
REPEAT 1691 1731 WD 25.
REPEAT 1733 1774 WD 26.
REPEAT 1775 1814 WD 27.
REPEAT 1887 1926 WD 28.
REPEAT 1932 1969 WD 29. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Polymorphism; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1969 AA |
Protein Sequence | MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICIW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120
LVSVGLDSKN AVCVWDWKRG KMLSMAPGHT DRIFDISWDL YQPNKLVSCG VKHIKFWSLC 180
GNALTPKRGV FGKTGDLQTI LCLACARDEL TYSGALNGDI YVWKGINLIR TIQGAHAAGI 240
FSMNACEEGF ATGGRDGCIR LWDLTFKPIT VIDLRETDQG YKGLSVRSVC WRGDHILVGT 300
QDSEIFEIVV QERNKPFLIM QGHCEGELWA LAVHPTKPLA VTGSDDRSVR IWSLVDHALI 360
ARCNMEEPIR CAAVNADGIH LALGMKDGSF TVLRVRDMTE VVHIKDRKEA IHELKYSPDG 420
TYLAVGCNDS SVDIYGVAQR YKKVGECLGS LSFITHLDWS SDSRYLQTND GNGKRLFYRM 480
PGGKEVTSTE EIKGVHWASW TCVSGLEVNG IWPKYSDIND INSVDGNYIG QVLVTADDYG 540
IIKLFRYPCL RKGAKFRKYI GHSAHVTNVR WSHDYQWVIS IGGADHSVFQ WKFIPERKLK 600
DAVHIAPQES LADSHSDESD SDLSDVPELD SEIEQETQLT YRRQVYKEDL PQLKEQCKEK 660
QKSATSKRRE RAPGNSIRLH FVHGYRGYDC RSNLFYTQIG EIVYHVAAVG VIYNRQQNTQ 720
RFYLGHDDDI LCLTIHPLKD YVATGQVGRD PSIHIWDTET IKPLSILKGH HQYGVSAVDF 780
SADGKRLASV GIDDSHTVVL WDWKKGEKLS IARGSKDKIF VVKMNPYVPD KLITAGIKHM 840
KFWRKAGGGL IGRKGYIGTL GKNDTMMCAV YGWTEEMAFS GTSTGDVCIW RDIFLVKTVK 900
AHDGPVFSMH ALEKGFVTGG KDGIVALWDD SFERCLKTYA IKRAALAPGS KGLLLEDNPS 960
IRAISLGHGH ILVGTKNGEI LEVDKSGPIT LLVQGHMEGE VWGLATHPYL PICATVSDDK 1020
TLRIWDLSPS HCMLAVRKLK KGGRCCCFSP DGKALAVGLN DGSFLMANAD TLEDLVSFHH 1080
RKDMISDIRF SPGSGKYLAV ASHDSFIDIY NVMSSKRVGI CKGATSYITH IDWDIRGKLL 1140
QVNTGAKEQL FFEAPRGKKQ TIPSVEVEKI AWASWTSVLG LCCEGIWPVI GEVTDVTASC 1200
LTSDKMVLAT GDDLGFVKLF RYPTKGKFGK FKRYVAHSTH VTNVRWTYDD SMLVTLGGTD 1260
MSLMVWTNEM EGYREKRPCD SEESDIDSEE DGGYDSDVTR ENEISYTIRA LSTNIRPMLG 1320
IKPHLQQKEP SIDERQGVVR GSRPPVSRAP PQPEKLQTNN VGKKKRPIED LVLELIFGYR 1380
GRDCRNNVHY LNDGDDIIYH TASVGILHNV ATGSQSFYQE HNDDILCLTV NQHPKFINIV 1440
ATGQVGDSAD MSATAPSIHI WDAMNKQTLS ILRCYHSKGV CSVSFSATGK LLLSVGLDPE 1500
HTITIWRWQE GAKIASRAGH NQRIFVAEFR PDSDTQFVSV GVKHVKFWTL AGRALLSKKG 1560
LLSTLEDARM QTMLAIAFGA NNLTFTGTIS GDVCVWKDHI LCRIVARAHN GPVFAMYTTL 1620
RDGLIVTGGK ERPSKEGGAV KLWDQELRRC RAFRLETGQA TDCVRSVCRG KGKILVGTRN 1680
AEIIEVGEKN AACNILVNGH VDGPIWGLAT HPSRDFFLSA AEDGTVRLWD IADKKMLNKV 1740
NLGHAARTVC YSPEGDMVAI GMKNGEFIIL LVSSLKIWGK KRDRRCAIHD IRFSPDSRYL 1800
AVGSSENSVD FYDLTLGPTL NRISYCKDIP SFVIQMDFSA DSSYLQVSSG CYKRHVYEVP 1860
SGKHLMDHAA IDRITWATWT SILGDEVLGI WSRHAEKADV NCACVSHSGI SLVTGDDFGM 1920
VKLFDFPCPE KFAKHKRFLG HSPHVTNIRF TSGDRHVVSA GGDDCSLFVW KCVHTPH 1977 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |