UniProt Accession

 DHRS1_MOUSE; Q99L04; Q3THW0; Q9D148 

Genbank Protein ID

 AK003958; AK146317; AK168115; AK168147; BC003930 

Genbank Nucleotide ID

 BAB23093.1; BAE27072.1; BAE40086.1; BAE40112.1; AAH03930.1 

Protein Name

 Dehydrogenase/reductase SDR family member 1 

Protein Synonyms/Alias

  

Gene Name

 Dhrs1 

Gene Synonyms/Alias

 D14ertd484e 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
6	**MVAPMKGQVCVVT	ubiquitination	[1]
72	SSQESEVKSLFEQVD	acetylation	[2]
83	EQVDREQKGRLDVLV	acetylation	[2]
83	EQVDREQKGRLDVLV	ubiquitination	[1]
207	MVKEFMAKEDTPEDP	ubiquitination	[1]
217	TPEDPLFKKMKPDFS	acetylation	[2]
265	LARRYGLKDIDGRPV	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

  

Sequence Annotation

 ACT_SITE 163 163 Proton acceptor (By similarity).
 BINDING 151 151 Substrate (By similarity).  

Keyword

 Complete proteome; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 313 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 

Interpro

 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF00106; adh_short 

SMART

  

PROSITE

 PS00061; ADH_SHORT 

PRINTS

 PR00081; GDHRDH.