CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008716
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein NRD1 
Protein Synonyms/Alias
  
Gene Name
 NRD1 
Gene Synonyms/Alias
 YNL251C; N0868 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
476SSKAISQKMPTDSGRacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Plays a role in sequence-specific regulation of nuclear pre-mRNA abundance. 
Sequence Annotation
 DOMAIN 1 153 CID.
 DOMAIN 339 409 RRM.
 MOD_RES 263 263 Phosphoserine.
 MOD_RES 265 265 Phosphoserine.
 MOD_RES 271 271 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 575 AA 
Protein Sequence
MQQDDDFQNF VATLESFKDL KSGISGSRIK KLTTYALDHI DIESKIISLI IDYSRLCPDS 60
HKLGSLYIID SIGRAYLDET RSNSNSSSNK PGTCAHAINT LGEVIQELLS DAIAKSNQDH 120
KEKIRMLLDI WDRSGLFQKS YLNAIRSKCF AMDISNNTAN TASQQLSLDP KQRSKQILSN 180
LKKSPPLNLN ISLPTDLTST DPAKQQAALF QVIAALQKHF KTLPSHTSVG TVAPPQAHTI 240
TEYGSRRERE RERERYNSRR NRSRSPPAPF SQPSTGRKDR YPSVAQDQYS IGAPNTTFGT 300
NNHHLYPDEL NVSNNPHYRP KPVSYDSTLP PDHIKVYSRT LFIGGVPLNM KEWDLANVLK 360
PFAEVQSVIL NNSRKHAFVK VYSRHEAENV LQNFNKDGAL PLRTRWGVGF GPRDCCDYQH 420
GYSIIPMHRL TDADKKWSVS AQWGGTSGQP LVTGIVFEEP DIIVGEGVSS KAISQKMPTD 480
SGRNGPRSGK PNKSGSISSI SPVPYGNAPL ASPPPQQYVQ PMMQQPYGYA PNQPLPSQGP 540
AAAAPPVPQQ QFDPTAQLNS LMNMLNQQQQ QQQQS 575 
Gene Ontology
 GO:0035649; C:Nrd1 complex; IDA:SGD.
 GO:0005634; C:nucleus; IC:SGD.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0019904; F:protein domain specific binding; IDA:SGD.
 GO:0001068; F:transcription regulatory region RNA binding; IDA:SGD.
 GO:0071041; P:antisense RNA transcript catabolic process; IMP:SGD.
 GO:0071034; P:CUT catabolic process; IMP:SGD.
 GO:0031124; P:mRNA 3'-end processing; IMP:SGD.
 GO:0071028; P:nuclear mRNA surveillance; IMP:SGD.
 GO:0031126; P:snoRNA 3'-end processing; IMP:SGD.
 GO:0034472; P:snRNA 3'-end processing; IMP:SGD.
 GO:0030847; P:termination of RNA polymerase II transcription, exosome-dependent; IDA:SGD.
 GO:0042780; P:tRNA 3'-end processing; IMP:SGD. 
Interpro
 IPR006569; CID_dom.
 IPR008942; ENTH_VHS.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00582; RPR
 SM00360; RRM 
PROSITE
 PS51391; CID
 PS50102; RRM 
PRINTS