| Tag | Content |
|---|
| CPLM ID | CPLM-024899 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pyruvate carboxylase |
Protein Synonyms/Alias | |
Gene Name | CG1516, Dmel_CG1516 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 187 | EEALEFCKKHGLPVI | acetylation | [1] | | 239 | NGAMFIEKFIERPRH | acetylation | [1] | | 1002 | GRPGAELKDLDFDKL | acetylation | [1] | | 1008 | LKDLDFDKLKKELQE | acetylation | [1] | | 1115 | ILDKEAVKEIHVHPK | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity). |
Sequence Annotation | |
Keyword | ATP-binding; Biotin; Complete proteome; Ligase; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1197 AA |
Protein Sequence | MFIPAAQSAY RTLRKTQPRV RLNAIFKNGY SSKVEYKPIR SVLVANRGEI AIRVFRACTE 60
LGIKSVAVYS EQDKMHMHRQ KADESYIVGK GLPPVEAYLN IPELIRVCKE NDVDAVHPGY 120
GFLSERSDFA QAVIDAGLRF IGPSPEVVQK MGDKVAARVA AIEAGVPIVP GTDGPVTTKE 180
EALEFCKKHG LPVIFKAAYG GGGRGMRVVR KMEDVEESFQ RASSEAKAAF GNGAMFIEKF 240
IERPRHIEVQ LLGDKAGNVV HLYERDCSVQ RRHQKVVEIA PAPRLPIEIR DKMTEAAVRL 300
ARHVGYENAG TVEFLCDESG NFYFIEVNAR LQVEHTVTEE ITGIDLVQSQ IRVAEGMTLP 360
ELGYTQDKIV PRGYAIQCRV TTEDPANDFQ PNTGRLEVFR SGEGMGIRLD SASAYAGAII 420
SPYYDSLLVK VISHASDLQS SASKMNRALR EFRIRGVKTN IPFLLNVLEN QKFLHGVLDT 480
YFIDEHPQLF KFKPSLNRAQ KLLNYMGEVL VNGPQTPLAT TLKPALVSPH VPEVPLDLSP 540
EAIEREERGE AKVTEPPKGL REVLVCEGPE AFAKEVRNRK ELLLMDTTFR DAHQSLLATR 600
VRSHDLLKIS PYVTHKFNNL YSLENWGGAT FDVALRFLHE CPWERLEEMR KRIPNIPFQM 660
LLRGANAVGY TSYPDNVVYK FCELAVQTGM DIFRVFDSLN YLPNLILGME AAGKAGGVVE 720
AAISYTGDVS DPKRTKYDLK YYTNLADELV KAGTHVLCIK DMAGLLKPES ARLLITAIRD 780
KHPDIPIHIH THDTSGAGVA SMLACANAGA DVVDVAVDSM SGMTSQPSMG AVVASLQGTP 840
LDTNLDLRTV SEYSAYWEQT RTLYAPFECT TTMRSGNADV YLNEIPGGQY TNLQFQAFSL 900
GLGDFFEDVK KAYREANLLL GDIIKVTPSS KVVGDLAQFM VQNDLTADQV LERAEELSFP 960
KSVVEYLQGS IGIPHGGFPE PLRSRVLKDM PRIEGRPGAE LKDLDFDKLK KELQESHTCV 1020
TNRDVMSAAL YPQVTNDFLN FREKYGPVDK LDTRIFLTGP KVGEEFDVPL ERGKTLSVKA 1080
LAVSADLKPN GIREVFFELN GQLRAVHILD KEAVKEIHVH PKANKSNKSE VGAPMPGTVI 1140
DIRVKVGDKV EKGQPLVVLS AMKMEMVVQS PLAGVVKKLE IANGTKLEGE DLIMIIE 1197 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |