| Tag | Content |
|---|
| CPLM ID | CPLM-018522 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier family 22 member 7 |
Protein Synonyms/Alias | Organic anion transporter 2; mOAT2 |
Gene Name | Slc22a7 |
Gene Synonyms/Alias | Oat2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 9 | GFEELLHKVGGFGPF | ubiquitination | [1] | | 319 | LSQEALNKVITMERV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mediates sodium-independent multispecific organic anion transport. High affinity transport of glutarate and prostaglandin E2 in a sodium-independent manner. Mediates also the uptake of alpha-ketoglutarate, p-aminohippuric acid, methotrexate, ochratoxin A, valproate, allopurinol and bumetanide. |
Sequence Annotation | |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 540 AA |
Protein Sequence | MGFEELLHKV GGFGPFQLRN LVLLALPRFL LPMHFLLPIF MAAVPAHHCA LPDAPANLSH 60
QDLWLKTHLP RETDGSFSSC LRFAYPQALP NVTLGTEVYN SGEPEGEPLT VPCSQGWEYD 120
RSEFSSTIAT EWDLVCEQRG LNKVTSTCFF IGVLLGAVVY GYLSDRFGRR RLLLVAYVST 180
LALGLMSAAS VNYIMFVTTR MLTGSALAGF TIIVLPLELE WLDVEHRTVA GVISTTFWTG 240
GVLLLTLVGY LIRSWRWLLL AATLPCVPGI ISIWWVPESA RWLLTQGRVE EAKKYLSICA 300
KLNGRPISED SLSQEALNKV ITMERVSQRP SYLDLFRTSQ LRHVSLCCMM MWFGVNFSYY 360
GLTLDASGLG LTVYQTQLLF GAVEVPSKIT VFFLVRLVGR RLTEAGMLLA TALTFGISLL 420
VSSDTKSWIT ALVVIGKAFS EAAFTTAYLF TSELYPTVLR QTGMGFTALI GRLGASLAPL 480
VVLLDGVWLL LPKLAYGGIS FLAACTVLLL PETKKAQLPE TIQDVERKGR KIDRSGTELA 540 |
Gene Ontology | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell. GO:0005887; C:integral to plasma membrane; TAS:MGI. GO:0008514; F:organic anion transmembrane transporter activity; IDA:MGI. GO:0035634; P:response to stilbenoid; IEP:UniProtKB. |
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SMART | |
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