CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021927
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myeloid leukemia factor 
Protein Synonyms/Alias
 Myelodysplasia-myeloid leukemia factor; dMLF 
Gene Name
 Mlf 
Gene Synonyms/Alias
 CG8295 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
166ERAHIIEKEQDMRSGacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 REGION 96 202 Interaction with DREF.
 MOD_RES 323 323 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 376 AA 
Protein Sequence
MSLFGALMGD FDDDLGLMNN HMNHTMNAMN MQMRSMNRLM NSFMPDPFMQ VSPFDQGFQQ 60
NALMERPQMP AMPAMGLFGM PMMPNFNRLL NADIGGNSGA SFCQSTVMTM SSGPDGRPQI 120
YQASTSTKTG PGGVRETRRT VQDSRTGVKK MAIGHHIGER AHIIEKEQDM RSGQLEERQE 180
FINLEEGEAE QFDREFTSRA SRGAVQSRHH AGGMQAIMPA RPAAHTSTLT IEPVEDDDDD 240
DDDCVIQEQQ PVRSSAGRHY SSAPTAPQNS GNIATAAAPT PTSSPTTYDT SNGNNNNYVS 300
SRRSYLRNGH GHSLATPRRP LRTPPSSPLA TVSTSPSIHP HPYAANPRRQ QRAVKHFHTE 360
DEAASSYKAV KRGKKK 376 
Gene Ontology
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.
 GO:0005705; C:polytene chromosome interband; IDA:FlyBase.
 GO:0050821; P:protein stabilization; IMP:FlyBase.
 GO:2000495; P:regulation of cell proliferation involved in compound eye morphogenesis; IEP:FlyBase.
 GO:0006355; P:regulation of transcription, DNA-dependent; IMP:FlyBase. 
Interpro
 IPR019376; Myeloid_leukemia_factor. 
Pfam
 PF10248; Mlf1IP 
SMART
  
PROSITE
  
PRINTS