| Tag | Content |
|---|
| CPLM ID | CPLM-017929 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 420 |
Protein Synonyms/Alias | |
Gene Name | ZNF420 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 198 | GEKPYACKECGKAFT | ubiquitination | [1] | | 230 | YKCEECGKAFIRSSQ | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 6 86 KRAB.
ZN_FING 139 161 C2H2-type 1.
ZN_FING 167 189 C2H2-type 2.
ZN_FING 195 217 C2H2-type 3.
ZN_FING 223 245 C2H2-type 4.
ZN_FING 251 273 C2H2-type 5.
ZN_FING 279 301 C2H2-type 6.
ZN_FING 307 329 C2H2-type 7.
ZN_FING 335 357 C2H2-type 8.
ZN_FING 363 385 C2H2-type 9.
ZN_FING 391 413 C2H2-type 10.
ZN_FING 419 441 C2H2-type 11.
ZN_FING 447 469 C2H2-type 12.
ZN_FING 475 497 C2H2-type 13.
ZN_FING 503 525 C2H2-type 14.
ZN_FING 531 553 C2H2-type 15.
ZN_FING 559 581 C2H2-type 16.
ZN_FING 587 609 C2H2-type 17.
ZN_FING 615 637 C2H2-type 18.
ZN_FING 643 665 C2H2-type 19. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 688 AA |
Protein Sequence | MARKLVMFRD VAIDFSQEEW ECLDSAQRDL YRDVMLENYS NLVSLDLPSR CASKDLSPEK 60
NTYETELSQW EMSDRLENCD LEESNSRDYL EAKGKMEKQQ ENQKEYFRQG MIIYDKMSIF 120
NQHTYLSQHS RCHSTEKPYK CKECGKAFRR ASHLTQHQSI HTGEKPYECK QCGKAFSRDS 180
QLSLHQRLHT GEKPYACKEC GKAFTQSSQL ILHHRIHTGE KPYKCEECGK AFIRSSQLTR 240
HQKVHTGEKP YECKECGKAF TQNSQLTLHQ RLHTGEKLYE CKECRKVFTQ LSQLILHKRI 300
HTGEKPYECK ECGKAFICGS QLSQHQKIHN GEKPYECKEC GRAFIRGSLL MQHQRIHTGE 360
KPYKCEECGK AFIRGSQLTQ HQRIHTNEKP YECKECGKMF SHGSQLTQHQ RIHTGEKPYQ 420
CKECGKAFNR GSLLTRHQRI HTGEKPYECK ECGKTFSRGS ELTQHERIHT GEKPYECKEC 480
GKSFIRGSQL TQHQRIHTGE KPYECKECRM AFTQSSHLSQ HQRLHTGEKP YVCNECGKAF 540
ARGLLLIQHQ RIHTGEKPYQ CKECGKAFIR GSQLTQHQRI HTGEKPYECK ECGKAFSHGS 600
QLTLHQRIHT GEKPYECREC RKAFTQSSHL SRHQRIHTGE KPYQCKECGK AFTRGSQLTQ 660
HQRIHISEKS FEYKECGIDF SHGSQVYM 688 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |