CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038390
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase RAD18 
Protein Synonyms/Alias
  
Gene Name
 Rad18 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
318RMRLEASKLNENVMVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 556 AA 
Protein Sequence
MEVLAEPRWP PGLAVMKTID DLLRCGICFE YFNIAVIIPQ CSHNYCSLCI RKFLSYKTQC 60
PTCCVAVTEP DLRNNRLLDE LVKSMNFART HLLQFALESP PISPVSSTSK KVVVKVHNAD 120
AAQHPVKQAN RLMDKFLIRE TGDCVFELLG KENERKFSPQ KELSTSAEIK ETSLLGKPVL 180
GLSDANGPVT PSTSTMKLDT KVSCPVCGVS IPENHINKHL DSCLSREEKK ESLRSSAHKR 240
KPLPKTVYNL LSDRDLKKKL KQYGLSVQGN KQQLIKRHQE FVHMYNAQCD ALHPKSAAEI 300
VQEIESMEKT RMRLEASKLN ENVMVFTKNQ TEKEIEEVHS EYHAGKQVAQ GCVSENKMRS 360
TIVCWQLSGK KHQNAFQLLV DQAKKGYKKT GRVSQAAAMR TDEPAETLPS MRTDEPAETL 420
PSMRTDEPAE TLPLMRADEP AETLPSECIA QEDNVSFSDT VSVTNHFPQP QLDSPGPSEP 480
ERPDDSSSCT DILFSSDSDS CNSSSSDIIR DLLEEEEAWE AAHKNDQNRE VSPQQTRRTR 540
ASECVEIEPR NKRNKN 556 
Gene Ontology
 GO:0000785; C:chromatin; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0005657; C:replication fork; IEA:Compara.
 GO:0001741; C:XY body; IDA:MGI.
 GO:0000403; F:Y-form DNA binding; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.
 GO:0006974; P:response to DNA damage stimulus; IMP:MGI.
 GO:0009411; P:response to UV; IMP:MGI.
 GO:0007283; P:spermatogenesis; IMP:MGI. 
Interpro
 IPR003034; SAP_dom.
 IPR006642; Znf_Rad18_put.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF02037; SAP 
SMART
 SM00184; RING
 SM00513; SAP
 SM00734; ZnF_Rad18 
PROSITE
 PS50800; SAP
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS