UniProt Accession

 DSBG_ECOLI; P77202 

Genbank Protein ID

 AF000956; U82598; U00096; AP009048 

Genbank Nucleotide ID

 AAC45785.1; AAB40805.1; AAC73705.2; BAA35234.2 

Protein Name

 Thiol:disulfide interchange protein DsbG 

Protein Synonyms/Alias

  

Gene Name

 dsbG 

Gene Synonyms/Alias

 ybdP; b0604; JW0597 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
185	QYEASGGKLKLNVPA	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Involved in disulfide bond formation. DsbG and DsbC are part of a periplasmic reducing system that controls the level of cysteine sulfenylation, and provides reducing equivalents to rescue oxidatively damaged secreted proteins such as ErfK, YbiS and YnhG. Probably also functions as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD. Displays chaperone activity in both redox states in vitro. 

Sequence Annotation

 DISULFID 126 129 Redox-active.  

Keyword

 3D-structure; Chaperone; Complete proteome; Direct protein sequencing; Disulfide bond; Periplasm; Redox-active center; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 248 AA 

Protein Sequence

Gene Ontology

 GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
 GO:0003756; F:protein disulfide isomerase activity; IMP:EcoliWiki.
 GO:0015035; F:protein disulfide oxidoreductase activity; IMP:EcoCyc. 

Interpro

 IPR018950; DiS-bond_isomerase_DsbC/G_N.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF13098; Thioredoxin_2 

SMART

  

PROSITE

 PS00194; THIOREDOXIN_1 

PRINTS