| Tag | Content |
|---|
| CPLM ID | CPLM-002462 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytochrome b-c1 complex subunit 2, mitochondrial |
Protein Synonyms/Alias | Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2 |
Gene Name | QCR2 |
Gene Synonyms/Alias | COR2; UCR2; YPR191W; P9677.6 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 115 | VLYKTAFKPHELTES | acetylation | [1] | | 173 | RVSLQDIKDFADKVY | acetylation | [1] | | 178 | DIKDFADKVYTKENL | acetylation | [1] | | 322 | SPAINYTKLKNAVQN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c. QCR2 is required for the assembly of the complex. |
Sequence Annotation | MOD_RES 141 141 Phosphoserine.
MOD_RES 168 168 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Respiratory chain; Transit peptide; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 368 AA |
Protein Sequence | MLSAARLQFA QGSVRRLTVS ARDAPTKIST LAVKVHGGSR YATKDGVAHL LNRFNFQNTN 60
TRSALKLVRE SELLGGTFKS TLDREYITLK ATFLKDDLPY YVNALADVLY KTAFKPHELT 120
ESVLPAARYD YAVAEQCPVK SAEDQLYAIT FRKGLGNPLL YDGVERVSLQ DIKDFADKVY 180
TKENLEVSGE NVVEADLKRF VDESLLSTLP AGKSLVSKSE PKFFLGEENR VRFIGDSVAA 240
IGIPVNKASL AQYEVLANYL TSALSELSGL ISSAKLDKFT DGGLFTLFVR DQDSAVVSSN 300
IKKIVADLKK GKDLSPAINY TKLKNAVQNE SVSSPIELNF DAVKDFKLGK FNYVAVGDVS 360
NLPYLDEL 368 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0030061; C:mitochondrial crista; IDA:SGD. GO:0005750; C:mitochondrial respiratory chain complex III; IDA:SGD. GO:0046872; F:metal ion binding; IEA:InterPro. GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. GO:0009060; P:aerobic respiration; IMP:SGD. GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IDA:SGD. GO:0006508; P:proteolysis; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |