CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002907
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 10 kDa chaperonin 
Protein Synonyms/Alias
 GroES protein; Protein Cpn10 
Gene Name
 groS 
Gene Synonyms/Alias
 groES; mopB; b4142; JW4102 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
15DRVIVKRKEVETKSAacetylation[1]
20KRKEVETKSAGGIVLacetylation[2]
34LTGSAAAKSTRGEVLacetylation[2]
55ILENGEVKPLDVKVGacetylation[1, 2]
60EVKPLDVKVGDIVIFacetylation[2]
74FNDGYGVKSEKIDNEacetylation[2]
Reference
 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. 
Sequence Annotation
 MOD_RES 34 34 N6-succinyllysine.  
Keyword
 3D-structure; Cell cycle; Cell division; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 97 AA 
Protein Sequence
MNIRPLHDRV IVKRKEVETK SAGGIVLTGS AAAKSTRGEV LAVGNGRILE NGEVKPLDVK 60
VGDIVIFNDG YGVKSEKIDN EEVLIMSESD ILAIVEA 97 
Gene Ontology
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0051082; F:unfolded protein binding; IMP:EcoCyc.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:HAMAP.
 GO:0009408; P:response to heat; IEP:EcoliWiki.
 GO:0019068; P:virion assembly; IMP:EcoliWiki. 
Interpro
 IPR020818; Chaperonin_Cpn10.
 IPR018369; Chaprnonin_Cpn10_CS.
 IPR011032; GroES-like. 
Pfam
 PF00166; Cpn10 
SMART
 SM00883; Cpn10 
PROSITE
 PS00681; CHAPERONINS_CPN10 
PRINTS
 PR00297; CHAPERONIN10.