| Tag | Content |
|---|
| CPLM ID | CPLM-006615 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription initiation factor IIE subunit beta |
Protein Synonyms/Alias | TFIIE-beta; Factor A 43 kDa subunit; Transcription factor A small subunit |
Gene Name | TFA2 |
Gene Synonyms/Alias | YKR062W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 3 | *****MSKNRDPLLA | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity). |
Sequence Annotation | DNA_BIND 113 187 TFIIE beta.
MOD_RES 97 97 Phosphoserine.
MOD_RES 106 106 Phosphoserine. |
Keyword | Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 328 AA |
Protein Sequence | MSKNRDPLLA NLNAFKSKVK SAPVIAPAKV GQKKTNDTVI TIDGNTRKRT ASERAQENTL 60
NSAKNPVLVD IKKEAGSNSS NAISLDDDDD DEDFGSSPSK KVRPGSIAAA ALQANQTDIS 120
KSHDSSKLLW ATEYIQKKGK PVLVNELLDY LSMKKDDKVI ELLKKLDRIE FDPKKGTFKY 180
LSTYDVHSPS ELLKLLRSQV TFKGISCKDL KDGWPQCDET INQLEEDSKI LVLRTKKDKT 240
PRYVWYNSGG NLKCIDEEFV KMWENVQLPQ FAELPRKLQD LGLKPASVDP ATIKRQTKRV 300
EVKKKRQRKG KITNTHMTGI LKDYSHRV 328 |
Gene Ontology | GO:0005673; C:transcription factor TFIIE complex; IDA:SGD. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006366; P:transcription from RNA polymerase II promoter; IDA:SGD. GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |