CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024189
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Prohibitin-2, mitochondrial 
Protein Synonyms/Alias
 Atphb2 
Gene Name
 PHB2 
Gene Synonyms/Alias
 At1g03860; F21M11.21 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
5***MSFNKVPNIPGAacetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031
Functional Description
 Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 286 AA 
Protein Sequence
MSFNKVPNIP GAPALSALLK VSVIGGLGVY ALTNSLYNVD GGHRAVMFNR LTGIKEKVYP 60
EGTHFMVPWF ERPIIYDVRA RPYLVESTTG SHDLQMVKIG LRVLTRPMGD RLPQIYRTLG 120
ENYSERVLPS IIHETLKAVV AQYNASQLIT QREAVSREIR KILTERASNF DIALDDVSIT 180
TLTFGKEFTA AIEAKQVAAQ EAERAKFIVE KAEQDRRSAV IRAQGEAKSA QLIGQAIANN 240
QAFITLRKIE AAREIAQTIA QSANKVYLSS NDLLLNLQEM NLEPKK 286 
Gene Ontology
 GO:0005618; C:cell wall; IDA:TAIR.
 GO:0009507; C:chloroplast; IDA:TAIR.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005747; C:mitochondrial respiratory chain complex I; IDA:TAIR.
 GO:0005774; C:vacuolar membrane; IDA:TAIR. 
Interpro
 IPR001107; Band_7.
 IPR000163; Prohibitin. 
Pfam
 PF01145; Band_7 
SMART
 SM00244; PHB 
PROSITE
  
PRINTS
 PR00679; PROHIBITIN.