CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043876
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Long-chain-fatty-acid--CoA ligase 3 
Protein Synonyms/Alias
  
Gene Name
 ACSL3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
133TLADQSSKIKKGSKGubiquitination[1, 2, 3]
162EIMDRIYKNVMNKVSubiquitination[2]
167IYKNVMNKVSEMSSFubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 213 AA 
Protein Sequence
TLFRPLLNET LQRRSPGFSI QIASIVIFSP CLASVFFIEN QPHSKPLPSD IAVIMYTSGS 60
TGLPKGVMIS HSNIIAGITG MAERIPELGE EDVYIGYLPL AHVLELSAEL VCLSHGCRIG 120
YSSPQTLADQ SSKIKKGSKG DTSMLKPTLM AAVPEIMDRI YKNVMNKVSE MSSFQRNLFI 180
LAYNYKMEQI SKGRNTPLCD SFVFRKVRSL LGG 213 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro. 
Interpro
 IPR020459; AMP-binding.
 IPR020845; AMP-binding_CS.
 IPR000873; AMP-dep_Synth/Lig. 
Pfam
 PF00501; AMP-binding 
SMART
  
PROSITE
 PS00455; AMP_BINDING 
PRINTS
 PR00154; AMPBINDING.