CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein SCAF11 
Protein Synonyms/Alias
  
Gene Name
 SCAF11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
93EHFGTSCKGYALAHTubiquitination[1]
106HTQEGEEKKQTSGTSubiquitination[2]
107TQEGEEKKQTSGTSNubiquitination[1]
898YRSSFAYKDQNENRWubiquitination[1]
934EQQSYKRKSEQEFSFubiquitination[1]
960ASSWAVRKTLPADVQubiquitination[1, 3]
986GPQSGWMKQEEETSGubiquitination[2]
1162KASNAAVKLAESKVSacetylation[4]
1200QEVKLAIKPFYQNKDacetylation[5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1271 AA 
Protein Sequence
MFSSVSHSGE SSFTYRAYCT EFIEASEISA LIRQKRHELE LSWFPDTLPG IGRIGFIPWN 60
VETEVLPLIS SVLPRTIFPT STISFEHFGT SCKGYALAHT QEGEEKKQTS GTSNTRGSRR 120
KPAMTTPTRR STRNTRAETA SQSQRSPISD NSGCDAPGNS NPSLSVPSSA ESEKQTRQAP 180
KRKSVRRGRK PPLLKKKLRS SVAAPEKSSS NDSVDEETAE SDTSPVLEKE HQPDVDSSNI 240
CTVQTHVENQ SANCLKSCNE QIEESEKHTA NYDTEERVGS SSSESCAQDL PVLVGEEGEV 300
KKLENTGIEA NVLCLESEIS ENILEKGGDP LEKQDQISGL SQSEVKTDVC TVHLPNDFPT 360
CLTSESKVYQ PVSCPLSDLS ENVESVVNEE KITESSLVEI TEHKDFTLKT EELIESPKLE 420
SSEGEIIQTV DRQSVKSPEV QLLGHVETED VEIIATCDTF GNEDFNNIQD SENNLLKNNL 480
LNTKLEKSLE EKNESLTEHP RSTELPKTHI EQIQKHFSED NNEMIPMECD SFCSDQNESE 540
VEPSVNADLK QMNENSVTHC SENNMPSSDL ADEKVETVSQ PSESPKDTID KTKKPRTRRS 600
RFHSPSTTWS PNKDTPQEKK RPQSPSPRRE TGKESRKSQS PSPKNESARG RKKSRSQSPK 660
KDIARERRQS QSRSPKRDTT RESRRSESLS PRRETSRENK RSQPRVKDSS PGEKSRSQSR 720
ERESDRDGQR RERERRTRKW SRSRSHSRSP SRCRTKSKSS SFGRIDRDSY SPRWKGRWAN 780
DGWRCPRGND RYRKNDPEKQ NENTRKEKND IHLDADDPNS ADKHRNDCPN WITEKINSGP 840
DPRTRNPEKL KESHWEENRN ENSGNSWNKN FGSGWVSNRG RGRGNRGRGT YRSSFAYKDQ 900
NENRWQNRKP LSGNSNSSGS ESFKFVEQQS YKRKSEQEFS FDTPADRSGW TSASSWAVRK 960
TLPADVQNYY SRRGRNSSGP QSGWMKQEEE TSGQDSSLKD QTNQQVDGSQ LPINMMQPQM 1020
NVMQQQMNAQ HQPMNIFPYP VGVHAPLMNI QRNPFNIHPQ LPLHLHTGVP LMQVATPTSV 1080
SQGLPPPPPP PPPSQQVNYI ASQPDGKQLQ GIPSSSHVSN NMSTPVLPAP TAAPGNTGMV 1140
QGPSSGNTSS SSHSKASNAA VKLAESKVSV AVEASADSSK TDKKLQIQEK AAQEVKLAIK 1200
PFYQNKDITK EEYKEIVRKA VDKVCHSKSG EVNSTKVANL VKAYVDKYKY SRKGSQKKTL 1260
EEPVSTEKNI G 1271 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS