CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038570
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Recombining-binding protein suppressor of hairless 
Protein Synonyms/Alias
  
Gene Name
 Rbpj 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
160SKKKQSLKNADLCIAacetylation[1]
300FQATPCPKEQNKEMIubiquitination[2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 485 AA 
Protein Sequence
MLAYRKFGER PPPKRLTREA MRNYLKERGD QTVLILHAKV AQKSYGNEKR FFCPPPCVYL 60
MGSGWKKKKE QMERDGCSEQ ESQPCAFIGI GNSDQEMQQL NLEGKNYCTA KTLYISDSDK 120
RKHFMLSVKM FYGNSDDIGV FLSKRIKVIS KPSKKKQSLK NADLCIASGT KVALFNRLRS 180
QTVSTRYLHV EGGNFHASSQ QWGAFYIHLL DDDESEGEEF TVRDGYIHYG QTVKLVCSVT 240
GMALPRLIIR KVDKQTALLD ADDPVSQLHK CAFYLKDTER MYLCLSQERI IQFQATPCPK 300
EQNKEMINDG ASWTIISTDK AEYTFYEGMG PVLAPVTPVP VVESLQLNGG GDVAMLELTG 360
QNFTPNLRVW FGDVEAETMY RCGESMLCVV PDISAFREGW RWVRQPVQVP VTLVRNDGVI 420
YSTSLTFTYT PEPGPRPHCS AAGAILRANS SQVPSNESNT NSEGNYTNAS TNSTSVTSST 480
ATVVS 485 
Gene Ontology
 GO:0005667; C:transcription factor complex; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:InterPro.
 GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISO:MGI.
 GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.
 GO:0001525; P:angiogenesis; IMP:MGI.
 GO:0009912; P:auditory receptor cell fate commitment; IMP:MGI.
 GO:0030183; P:B cell differentiation; IMP:MGI.
 GO:0042742; P:defense response to bacterium; IMP:MGI.
 GO:0009957; P:epidermal cell fate specification; IMP:MGI.
 GO:0001837; P:epithelial to mesenchymal transition; IMP:MGI.
 GO:0048820; P:hair follicle maturation; IMP:MGI.
 GO:0007507; P:heart development; IMP:MGI.
 GO:0006959; P:humoral immune response; IMP:MGI.
 GO:0002437; P:inflammatory response to antigenic stimulus; IMP:MGI.
 GO:0072602; P:interleukin-4 secretion; IMP:MGI.
 GO:0030216; P:keratinocyte differentiation; IMP:MGI.
 GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0021983; P:pituitary gland development; IMP:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
 GO:0007221; P:positive regulation of transcription of Notch receptor target; IGI:MGI.
 GO:0048505; P:regulation of timing of cell differentiation; IMP:MGI.
 GO:0048733; P:sebaceous gland development; IMP:MGI.
 GO:0035019; P:somatic stem cell maintenance; IMP:MGI. 
Interpro
 IPR015350; Beta-trefoil_DNA-bd_dom.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002909; IPT_TIG_rcpt.
 IPR015351; LAG1_DNA-bd.
 IPR008967; p53-like_TF_DNA-bd. 
Pfam
 PF09270; BTD
 PF09271; LAG1-DNAbind
 PF01833; TIG 
SMART
  
PROSITE
  
PRINTS