UniProt Accession

 J3QL45_HUMAN; J3QL45 

Genbank Protein ID

 AC118344 

Genbank Nucleotide ID

  

Protein Name

 RAC-beta serine/threonine-protein kinase 

Protein Synonyms/Alias

  

Gene Name

 AKT2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
96	KKLLPPFKPQVTSEV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 106 AA 

Protein Sequence

Gene Ontology

 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
 GO:0032859; P:activation of Ral GTPase activity; IEA:Compara.
 GO:0008286; P:insulin receptor signaling pathway; IEA:Compara.
 GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Compara.
 GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IEA:Compara.
 GO:0072659; P:protein localization to plasma membrane; IEA:Compara.
 GO:0046328; P:regulation of JNK cascade; IEA:Compara. 

Interpro

 IPR000961; AGC-kinase_C.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom. 

Pfam

 PF00069; Pkinase 

SMART

  

PROSITE

 PS51285; AGC_KINASE_CTER
 PS50011; PROTEIN_KINASE_DOM 

PRINTS