UniProt Accession

 B4DFC0_HUMAN; B4DFC0 

Genbank Protein ID

 AC055860; AC124058; AC124078; AK294022 

Genbank Nucleotide ID

 BAG57381.1 

Protein Name

 Secretion-regulating guanine nucleotide exchange factor 

Protein Synonyms/Alias

 cDNA FLJ59192, highly similar to Secretion-regulating guanine nucleotide exchange factor 

Gene Name

 SERGEF 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
87	LPLFFTAKEPSRVTG	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 174 AA 

Protein Sequence

Gene Ontology

 GO:0050709; P:negative regulation of protein secretion; IEA:InterPro. 

Interpro

 IPR027048; DelGEF.
 IPR009091; RCC1/BLIP-II.
 IPR000408; Reg_chr_condens. 

Pfam

 PF00415; RCC1 

SMART

  

PROSITE

 PS50012; RCC1_3 

PRINTS

 PR00633; RCCNDNSATION.