UniProt Accession

 RL6A_YEAST; Q02326; D6VZA0 

Genbank Protein ID

 D10225; Z46373; BK006946 

Genbank Nucleotide ID

 BAA01077.1; CAA86505.1; DAA09824.1 

Protein Name

 60S ribosomal protein L6-A 

Protein Synonyms/Alias

 L17; RP18; YL16 

Gene Name

 RPL6A 

Gene Synonyms/Alias

 RPL17A; YL16A; YML073C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
8	MSAQKAPKWYPSEDV	acetylation	[1]
8	MSAQKAPKWYPSEDV	ubiquitination	[2]
19	SEDVAALKKTRKAAR	acetylation	[1]
19	SEDVAALKKTRKAAR	ubiquitination	[2, 3]
29	RKAARPQKLRASLVP	ubiquitination	[2]
70	LLISGPFKVNGVPLR	acetylation	[1]
117	KLTKKEKKEANLFPE	ubiquitination	[2]
128	LFPEQQNKEIKAERV	ubiquitination	[2, 3]
131	EQQNKEIKAERVEDQ	acetylation	[1]
143	EDQKVVDKALIAEIK	ubiquitination	[3]
170	FSLKNGDKPHMLKF*	ubiquitination	[2]
175	GDKPHMLKF******	acetylation	[1]
175	GDKPHMLKF******	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

  

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.
 MOD_RES 12 12 Phosphoserine.  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 176 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IDA:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IMP:SGD. 

Interpro

 IPR014722; Rib_L2_dom2.
 IPR000915; Ribosomal_L6E. 

Pfam

 PF01159; Ribosomal_L6e 

SMART

  

PROSITE

 PS01170; RIBOSOMAL_L6E 

PRINTS