CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043127
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 G2/mitotic-specific cyclin-B2 
Protein Synonyms/Alias
  
Gene Name
 CCNB2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
232KVNENLTKFIAIKNKubiquitination[1]
239KFIAIKNKYASSKLLubiquitination[2]
260QLNSKAVKDLASPLIubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] A data set of human endogenous protein ubiquitination sites.
 Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J.
 Mol Cell Proteomics. 2011 May;10(5):M110.002089. [PMID: 20972266]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Cell cycle; Cell division; Complete proteome; Cyclin; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 270 AA 
Protein Sequence
MALLRRPTGP SPTPEDVSMK EENLCQAFSD ALLCKIEDID NEDWENPQLC SDYVKDIYQY 60
LRQLEVLQSI NPHFLDGRDI NGRMRAILVD WLVQVHSKFR LLQETLYMCV GIMDRFLQVQ 120
PVSRKKLQLV GITALLLASK YEEMFSPNIE DFVYITDNAY TSSQIREMET LILKELKFEL 180
GRPLPLHFLR RASKAGENLK QQYYTGYTEN EVLEVMQHMA KNVVKVNENL TKFIAIKNKY 240
ASSKLLKISM IPQLNSKAVK DLASPLIGRS 270 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro. 
Interpro
 IPR013763; Cyclin-like.
 IPR014400; Cyclin_A/B/D/E.
 IPR004367; Cyclin_C-dom.
 IPR006671; Cyclin_N. 
Pfam
 PF02984; Cyclin_C
 PF00134; Cyclin_N 
SMART
 SM00385; CYCLIN 
PROSITE
 PS00292; CYCLINS 
PRINTS