| Tag | Content |
|---|
| CPLM ID | CPLM-003960 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nuclear fusion protein FUS1 |
Protein Synonyms/Alias | |
Gene Name | FUS1 |
Gene Synonyms/Alias | YCL027W; YCL27W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 147 | YSNRDIEKYNDTQWT | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Required for cell fusion. Negatively regulates Sho1p signaling to ensure efficient cell fusion. |
Sequence Annotation | DOMAIN 436 512 SH3.
REGION 97 512 Hydrophilic.
MOD_RES 178 178 Phosphothreonine.
MOD_RES 190 190 Phosphoserine.
MOD_RES 256 256 Phosphoserine.
MOD_RES 281 281 Phosphothreonine.
MOD_RES 424 424 Phosphothreonine. |
Keyword | Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; SH3 domain; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 512 AA |
Protein Sequence | MVATIMQTTT TVLTTVAAMS TTLASNYISS QASSSTSVTT VTTIATSIRS TPSNLLFSNV 60
AAQPKSSSAS TIGLSIGLPI GIFCFGLLIL LCYFYLKRNS VSISNPPMSA TIPREEEYCR 120
RTNWFSRLFW QSKCEDQNSY SNRDIEKYND TQWTSGDNMS SKIQYKISKP IIPQHILTPK 180
KTVKNPYAWS GKNISLDPKV NEMEEEKVVD AFLYTKPPNI VHIESSMPSY NDLPSQKTVS 240
SKKTALKTSE KWSYESPLSR WFLRGSTYFK DYGLSKTSLK TPTGAPQLKQ MKMLSRISKG 300
YFNESDIMPD ERSPILEYNN TPLDANDSVN NLGNTTPDSQ ITSYRNNNID LITARPHSVI 360
YGTTAQQTLE TNFNDHHDCN KSTEKHELII PTPSKPLKKR KKRRQSKMYQ HLQHLSRSKP 420
LPLTPNSKYN GEASVQLGKT YTVIQDYEPR LTDEIRISLG EKVKILATHT DGWCLVEKCN 480
TQKGSIHVSV DDKRYLNEDR GIVPGDCLQE YD 512 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IDA:SGD. GO:0043332; C:mating projection tip; IDA:SGD. GO:0032065; P:cortical protein anchoring; IMP:SGD. GO:0000755; P:cytogamy; IMP:SGD. GO:0031385; P:regulation of termination of mating projection growth; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |