CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025285
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial 
Protein Synonyms/Alias
 RIKEN cDNA 1500032D16, isoform CRA_a 
Gene Name
 Ndufv3 
Gene Synonyms/Alias
 1500032D16Rik; mCG_14261 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
46SEKSAKEKELHPKTQacetylation[1]
188KGKAGSSKPEASRPLacetylation[1]
207PKITVSAKEKAKVQKacetylation[2]
207PKITVSAKEKAKVQKsuccinylation[2]
231KTLQPKKKWTKPVEDacetylation[1]
234QPKKKWTKPVEDSKEacetylation[1, 2]
234QPKKKWTKPVEDSKEsuccinylation[2]
262EMLEQNVKEEHQRGKacetylation[1]
281KTGKESAKPCEAEGIacetylation[1]
341KVPEPGWKTSSPLLRacetylation[2]
341KVPEPGWKTSSPLLRsuccinylation[2]
371QEVLEDQKPVSYSKTacetylation[1, 3]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 468 AA 
Protein Sequence
MAVSLLLRGG RIRALKAVLL EARVFPGELV SVVRLSTESE KSAKEKELHP KTQSVLKDVG 60
AEERGKLLTA HTAAALSKNS PPPSSYPSVE NTGGAVAGPH PGGSLLPTDE GLPKHLSRKT 120
LVAFPQKVMP PPQARGSDSK AQGHVQKVTN DSSSSSSSSS SDSDSDGEEH DSDRAPRVAS 180
KGKAGSSKPE ASRPLTTGAP KITVSAKEKA KVQKPPTDVT YPEKTLQPKK KWTKPVEDSK 240
EARSKPVTSR PQSSEMLEQN VKEEHQRGKP RPDKTGKESA KPCEAEGILP SHGKVRVPTQ 300
PTSGPVPTTQ IQEASAEHPP AVAPRKGARY PEPKVPEPGW KTSSPLLRKE SAEKQVPEGG 360
SQVQEVLEDQ KPVSYSKTLP VQEKDTVEES ARPHLEGRFQ VAVEAPPTDA VLPQEAPADT 420
QEPEPTDTTT YKNLQHHDYN TYTFLDLNLD LSKFRLPQPS SGRESPRH 468 
Gene Ontology
 GO:0005747; C:mitochondrial respiratory chain complex I; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI. 
Interpro
 IPR026193; NDUFV3. 
Pfam
  
SMART
  
PROSITE
  
PRINTS