UniProt Accession

 E9Q2K4_MOUSE; E9Q2K4 

Genbank Protein ID

 AC132587 

Genbank Nucleotide ID

  

Protein Name

 Actin-related protein 2/3 complex subunit 5 

Protein Synonyms/Alias

  

Gene Name

 Gm16372 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
86	LKVLISFKANDIEKA	ubiquitination	[1]
92	FKANDIEKAVQSLDK	acetylation	[2]
92	FKANDIEKAVQSLDK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 150 AA 

Protein Sequence

Gene Ontology

 GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
 GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro. 

Interpro

 IPR006789; ARP2/3_p16_Arc. 

Pfam

 PF04699; P16-Arc 

SMART

  

PROSITE

  

PRINTS