CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027250
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribose-phosphate pyrophosphokinase 
Protein Synonyms/Alias
  
Gene Name
 Prps1l1 
Gene Synonyms/Alias
 1700011K15Rik; mCG_48722 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
5***MPNIKLFSGSSHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Magnesium; Metal-binding; Nucleotide biosynthesis; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MPNIKLFSGS SHQDLSQKIT ERLGLELSKV VTKKFSNQET CVEIGESVRG EDVYIVQSGC 60
GEINDSLMEL LIMINACKIA SASRVTAVIP CFPYARQDKK DKSRAPISAK LVANMLSIAG 120
ADHIITMDLH ASQIQGFFDI PVDNLYAEPA VLKWIKENIS DWRNCTIVSP DAGGAKRVTS 180
IADHLNVDFA LIHKERKKAN EVDRMVLVGD VKDRVAILVD DMADTCGTIC YAADKLLSEG 240
ATRVYAILTH GIFSGPAIAR INGACFEAVV VTNTIPQEDK MKQCSKIQVI DIAMILAEAI 300
RRTHNGESVS YLFSHVPL 318 
Gene Ontology
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
 GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
 GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro. 
Interpro
 IPR000842; PRib_PP_synth_CS.
 IPR000836; PRibTrfase_dom.
 IPR005946; Rib-P_diPkinase. 
Pfam
 PF00156; Pribosyltran 
SMART
  
PROSITE
 PS00114; PRPP_SYNTHASE 
PRINTS