CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038971
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Trpc7 
Protein Synonyms/Alias
 Transient receptor potential cation channel, subfamily C, member 7 
Gene Name
 Trpc7 
Gene Synonyms/Alias
 rCG_24244 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
116ALLLAISKGYVRIVEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Ion channel; Ion transport; Membrane; Receptor; Reference proteome; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 862 AA 
Protein Sequence
MLGSNTFKNM QRRHTTLREK GRRQAIRGPA YMFNEKGTSL TPEEERFLDS AEYGNIPVVR 60
KMLEESKTLN FNCVDYMGQN ALQLAVGNEH LEVTELLLKK ENLARVGDAL LLAISKGYVR 120
IVEAILSHPA FAQGQRLTLS PLEQELRDDD FYAYDEDGTR FSHDITPIIL AAHCQEYEIV 180
HILLLKGARI ERPHDYFCKC NECTEKQRKD SFSHSRSRMN AYKGLASAAY LSLSSEDPVL 240
TALELSNELA RLANIETEFK NDYRKLSMQC KDFVVGVLDL CRDTEEVEAI LNGDVNLQVW 300
SDHHRPSLSR IKLAIKYEVK KFVAHPNCQQ QLLTMWYENL SGLRQQSIAV KFLAVFGVSI 360
GLPFLAIAYW IAPCSKLGRT LRSPFMKFVA HAVSFTIFLG LLVVNASDRF EGVKTLPNET 420
FTDYPKQIFR VKTTQFSWTE MLIMKWVLGM IWSECKEIWE EGPREYVLHL WNLLDFGMLS 480
VFVASFTARF MAFLKASEAQ LYVDQYVQDV TLHNVSLPPE VAYFTYARDK WWPSDPQIIS 540
EGLYAIAVVL SFSRIAYILP ANESFGPLQI SLGRTVKDIF KFMVIFIMVF VAFMIGMFNL 600
YSYYRGAKYN PAFTTVEESF KTLFWSIFGL SEVISVVLKY DHKFIENIGY VLYGVYNVTM 660
VVVLLNMLIA MINNSYQEIE EDADVEWKFA RAKLWLSYFD EGRTLPAPFN LVPSPKSFYY 720
LIMRIKMCLI KLCKSKAKRC ENDLEMGMLN SKFRKTRYQA GMRNSENLTA NSTFSKPTRY 780
QKIMKRLIKR YVLKAQVDRE NDEVNEGELK EIKQDISSLR YELLEEKSQA TGELADLIQQ 840
LSEKFGKNLN KDHLRVNKGK DI 862 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
 GO:0005262; F:calcium channel activity; IEA:Compara.
 GO:0005261; F:cation channel activity; TAS:RGD.
 GO:0006828; P:manganese ion transport; IEA:Compara. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR005821; Ion_trans_dom.
 IPR004729; TRP_channel.
 IPR013555; TRP_dom.
 IPR005463; TRPC7_channel.
 IPR002153; TRPC_channel. 
Pfam
 PF12796; Ank_2
 PF00520; Ion_trans
 PF08344; TRP_2 
SMART
 SM00248; ANK 
PROSITE
  
PRINTS
 PR01097; TRNSRECEPTRP.
 PR01648; TRPCHANNEL7.